Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1016/j.exphem.2016.01.003 http://scihub22266oqcxt.onion/10.1016/j.exphem.2016.01.003 C4852701!4852701!26806720     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Exp+Hematol 2016 ; 44 (4): 213-22 Nephropedia Template TP {{tp|p=26806720|t=2016. Macrophages: Key Regulators of Steady State and Demand-Adapted Hematopoiesis |pdf=|usr=}}{{26806720}} gab.com Text Macrophages: Key Regulators of Steady State and Demand-Adapted Hematopoiesis JO: Exp Hematol http://www.kidney.de/pget.php?&tw=1&pmid=26806720 #FOAvip Hematopoietic stem cell (HSC) function is required for balanced blood production throughout life, thus it is essential to understand the mechanisms regulating this highly dynamic process. Bone marrow-resident macrophages (M?s) have recently emerged as an important component of the HSC niche where they contribute to regulating HSC and progenitor cell (HSPC) mobilization and function. Here we review the role of M?s on immune cell production, HSPC pool size, and mobilization at steady state and under inflammatory conditions. Inflammation induces marked changes in hematopoiesis to restrict or promote generation of specific cell lineages, and this often has a negative impact on hematopoietic stem cell (HSC) function. Cytokines and growth factors induced during inflammation influence hematopoiesis by acting directly on HSPCs and/or by modulating niche cell function. We focus particular attention on the opposing effects of two key inflammatory proteins, interferon gamma (IFN?) and granulocyte-colony stimulating factor (G-CSF), in regulating bone marrow-resident M?s and HSPCs. M?s are essential for tissue homeostasis, and here we highlight their emerging role as a central regulator of both steady state and demand-adapted hematopoiesis. Twit Text FOAVip Macrophages: Key Regulators of Steady State and Demand-Adapted Hematopoiesis ????Exp Hematol http://www.kidney.de/pget.php?&tw=1&pmid=26806720 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26806720 #FOAvip English Wikipedia <ref>{{Cite pmid|26806720}}</ref> Macrophages: Key Regulators of Steady State and Demand-Adapted Hematopoiesis #MMPMID26806720 McCabe A; MacNamara KC Exp Hematol 2016[Apr]; 44 (4): 213-22 PMID26806720show ga Hematopoietic stem cell (HSC) function is required for balanced blood production throughout life, thus it is essential to understand the mechanisms regulating this highly dynamic process. Bone marrow-resident macrophages (M?s) have recently emerged as an important component of the HSC niche where they contribute to regulating HSC and progenitor cell (HSPC) mobilization and function. Here we review the role of M?s on immune cell production, HSPC pool size, and mobilization at steady state and under inflammatory conditions. Inflammation induces marked changes in hematopoiesis to restrict or promote generation of specific cell lineages, and this often has a negative impact on hematopoietic stem cell (HSC) function. Cytokines and growth factors induced during inflammation influence hematopoiesis by acting directly on HSPCs and/or by modulating niche cell function. We focus particular attention on the opposing effects of two key inflammatory proteins, interferon gamma (IFN?) and granulocyte-colony stimulating factor (G-CSF), in regulating bone marrow-resident M?s and HSPCs. M?s are essential for tissue homeostasis, and here we highlight their emerging role as a central regulator of both steady state and demand-adapted hematopoiesis. äMacrophages: Key Regulators of Steady State and Demand-Adapted Hematop(epmc).pdf DeepDyve Pubget Overpricing