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10.1590/0100-3984.2014.0062

http://scihub22266oqcxt.onion/10.1590/0100-3984.2014.0062
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C4851482!4851482!27141134
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suck abstract from ncbi


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pmid27141134      Radiol+Bras 2016 ; 49 (2): 112-6
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  • High-resolution computed tomography and histopathological findings in hypersensitivity pneumonitis: a pictorial essay* #MMPMID27141134
  • Torres PPTe S; Moreira MAR; Silva DGST; da Gama RRM; Sugita DM; Moreira MAdo C
  • Radiol Bras 2016[Mar]; 49 (2): 112-6 PMID27141134show ga
  • Hypersensitivity pneumonitis is a diffuse interstitial and granulomatous lung disease caused by the inhalation of any one of a number of antigens. The objective of this study was to illustrate the spectrum of abnormalities in high-resolution computed tomography and histopathological findings related to hypersensitivity pneumonitis. We retrospectively evaluated patients who had been diagnosed with hypersensitivity pneumonitis (on the basis of clinical-radiological or clinical-radiological-pathological correlations) and had undergone lung biopsy. Hypersensitivity pneumonitis is clinically divided into acute, subacute, and chronic forms; high-resolution computed tomography findings correlate with the time of exposure; and the two occasionally overlap. In the subacute form, centrilobular micronodules, ground-glass opacities, and air trapping are characteristic high-resolution computed tomography findings, whereas histopathology shows lymphocytic inflammatory infiltrates, bronchiolitis, variable degrees of organizing pneumonia, and giant cells. In the chronic form, high-resolution computed tomography shows traction bronchiectasis, honeycombing, and lung fibrosis, the last also being seen in the biopsy sample. A definitive diagnosis of hypersensitivity pneumonitis can be made only through a multidisciplinary approach, by correlating clinical findings, exposure history, high-resolution computed tomography findings, and lung biopsy findings.
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