Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 263.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 263.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 263.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26668338
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Clin+Infect+Dis
2016 ; 62
(6
): 707-713
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Emerging Cases of Powassan Virus Encephalitis in New England: Clinical
Presentation, Imaging, and Review of the Literature
#MMPMID26668338
Piantadosi A
; Rubin DB
; McQuillen DP
; Hsu L
; Lederer PA
; Ashbaugh CD
; Duffalo C
; Duncan R
; Thon J
; Bhattacharyya S
; Basgoz N
; Feske SK
; Lyons JL
Clin Infect Dis
2016[Mar]; 62
(6
): 707-713
PMID26668338
show ga
BACKGROUND: Powassan virus (POWV) is a rarely diagnosed cause of encephalitis in
the United States. In the Northeast, it is transmitted by Ixodes scapularis, the
same vector that transmits Lyme disease. The prevalence of POWV among animal
hosts and vectors has been increasing. We present 8 cases of POWV encephalitis
from Massachusetts and New Hampshire in 2013-2015. METHODS: We abstracted
clinical and epidemiological information for patients with POWV encephalitis
diagnosed at 2 hospitals in Massachusetts from 2013 to 2015. We compared their
brain imaging with those in published findings from Powassan and other viral
encephalitides. RESULTS: The patients ranged in age from 21 to 82 years, were,
for the most part, previously healthy, and presented with syndromes of fever,
headache, and altered consciousness. Infections occurred from May to September
and were often associated with known tick exposures. In all patients,
cerebrospinal fluid analyses showed pleocytosis with elevated protein. In 7 of 8
patients, brain magnetic resonance imaging demonstrated deep foci of increased
T2/fluid-attenuation inversion recovery signal intensity. CONCLUSIONS: We
describe 8 cases of POWV encephalitis in Massachusetts and New Hampshire in
2013-2015. Prior to this, there had been only 2 cases of POWV encephalitis
identified in Massachusetts. These cases may represent emergence of this virus in
a region where its vector, I. scapularis, is known to be prevalent or may
represent the emerging diagnosis of an underappreciated pathogen. We recommend
testing for POWV in patients who present with encephalitis in the spring to fall
in New England.