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10.28092/j.issn.2095-3941.2016.0003 http://scihub22266oqcxt.onion/10.28092/j.issn.2095-3941.2016.0003 C4850120!4850120!27144059     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Cancer+Biol+Med 2016 ; 13 (1): 12-8 Nephropedia Template TP {{tp|p=27144059|t=2016. Changing paradigm of cancer therapy: precision medicine by next-generation sequencing |pdf=|usr=}}{{27144059}} gab.com Text Changing paradigm of cancer therapy: precision medicine by next-generation sequencing JO: Cancer Biol Med http://www.kidney.de/pget.php?&tw=1&pmid=27144059 #FOAvip Precision medicine aims to identify the right drug, for the right patient, at the right dose, at the right time, which is particularly important in cancer therapy. Problems such as the variability of treatment response and resistance to medication have been long-standing challenges in oncology, especially for development of new medications. Solid tumors, unlike hematologic malignancies or brain tumors, are remarkably diverse in their cellular origins and developmental timing. The ability of next-generation sequencing (NGS) to analyze the comprehensive landscape of genetic alterations brings promises to diseases that have a highly complex and heterogeneous genetic composition such as cancer. Here we provide an overview of how NGS is able to facilitate precision medicine and change the paradigm of cancer therapy, especially for solid tumors, through technical advancements, molecular diagnosis, response monitoring and clinical trials. Twit Text FOAVip Changing paradigm of cancer therapy: precision medicine by next-generation sequencing ????Cancer Biol Med http://www.kidney.de/pget.php?&tw=1&pmid=27144059 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27144059 #FOAvip English Wikipedia <ref>{{Cite pmid|27144059}}</ref> Changing paradigm of cancer therapy: precision medicine by next-generation sequencing #MMPMID27144059 Xue Y; Wilcox WR Cancer Biol Med 2016[Mar]; 13 (1): 12-8 PMID27144059show ga Precision medicine aims to identify the right drug, for the right patient, at the right dose, at the right time, which is particularly important in cancer therapy. Problems such as the variability of treatment response and resistance to medication have been long-standing challenges in oncology, especially for development of new medications. Solid tumors, unlike hematologic malignancies or brain tumors, are remarkably diverse in their cellular origins and developmental timing. The ability of next-generation sequencing (NGS) to analyze the comprehensive landscape of genetic alterations brings promises to diseases that have a highly complex and heterogeneous genetic composition such as cancer. Here we provide an overview of how NGS is able to facilitate precision medicine and change the paradigm of cancer therapy, especially for solid tumors, through technical advancements, molecular diagnosis, response monitoring and clinical trials. äChanging paradigm of cancer therapy: precision medicine by next-genera(epmc).pdf DeepDyve Pubget Overpricing