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2016 ; 24
(ä): 61
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Coma of unknown origin in the emergency department: implementation of an in-house
management routine
#MMPMID27121376
Braun M
; Schmidt WU
; Möckel M
; Römer M
; Ploner CJ
; Lindner T
Scand J Trauma Resusc Emerg Med
2016[Apr]; 24
(ä): 61
PMID27121376
show ga
BACKGROUND: Coma of unknown origin is an emergency caused by a variety of
possibly life-threatening pathologies. Although lethality is high, there are
currently no generally accepted management guidelines. METHODS: We implemented a
new interdisciplinary standard operating procedure (SOP) for patients presenting
with non-traumatic coma of unknown origin. It includes a new in-house triage
process, a new alert call, a new composition of the clinical response team and a
new management algorithm (altogether termed "coma alarm"). It is triggered by two
simple criteria to be checked with out-of-hospital emergency response teams
before the patient arrives. A neurologist in collaboration with an internal
specialist leads the in-hospital team. Collaboration with anaesthesiology, trauma
surgery and neurosurgery is organised along structured pathways that include
standardised laboratory tests and imaging. Patients were prospectively enrolled.
We calculated response times as well as sensitivity and false positive rates,
thus proportions of over- and undertriaged patients, as quality measures for the
implementation in the SOP. RESULTS: During 24 months after implementation, we
identified 325 eligible patients. Sensitivity was 60 % initially (months 1-4),
then fluctuated between 84 and 94 % (months 5-24). Overtriage never exceeded
15 % and undertriage could be kept low at a maximum of 11 % after a learning
period. We achieved a median door-to-CT time of 20 minutes. 85 % of patients
needed subsequent ICU treatment, 40 % of which required specialised neuro-ICUs.
DISCUSSION: Our results indicate that our new simple in-house triage criteria may
be sufficient to identify eligible patients before arrival. We aimed at ensuring
the fastest possible proceedings given high portions of underlying time-sensitive
neurological and medical pathologies while using all available resources as
purposefully as possible. CONCLUSIONS: Our SOP may provide an appropriate tool
for efficient management of patients with non-traumatic coma. Our results justify
the assignment of the initial diagnostic workup to neurologists and internal
specialists in collaboration with anaesthesiologists.
|*Algorithms
[MESH]
|Adolescent
[MESH]
|Adult
[MESH]
|Aged
[MESH]
|Aged, 80 and over
[MESH]
|Coma/*diagnosis/mortality/therapy
[MESH]
|Emergency Medical Services/*organization & administration
[MESH]