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10.3402/jchimp.v6.30632

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suck abstract from ncbi


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pmid27124161
      J+Community+Hosp+Intern+Med+Perspect 2016 ; 6 (2 ): 30632
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  • Hydralazine-induced pauci-immune glomerulonephritis: intriguing case series with misleading diagnoses #MMPMID27124161
  • Babar F ; Posner JN ; Obah EA
  • J Community Hosp Intern Med Perspect 2016[]; 6 (2 ): 30632 PMID27124161 show ga
  • Hydralazine has been used since the 1950s for the management of hypertension. Evidence for hydralazine-associated vasculitis dates to pre-ANCA (antineutrophil cytoplasmic antibodies) era. This abstract describes two cases of ANCA-positive pauci-immune glomerulonephritis (GN) in challenging scenarios where diagnosis was misconstrued. A comprehensive literature review was done to understand the pathogenesis of drug-induced pauci-immune GN. We have described key diagnostic features that are helpful in distinguishing idiopathic ANCA vasculitis from drug-induced vasculitis. Additionally, we have also described different treatments meant to provide therapy options with the least side effects.
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