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2016 ; 9
(ä): 95-103
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gab.com Text
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Prevention of catheter-related bloodstream infections in patients on
hemodialysis: challenges and management strategies
#MMPMID27143948
Soi V
; Moore CL
; Kumbar L
; Yee J
Int J Nephrol Renovasc Dis
2016[]; 9
(ä): 95-103
PMID27143948
show ga
Catheter-related bloodstream infections are a significant source of morbidity and
mortality in the end-stage renal disease population. Although alternative
accesses to undergoing renal replacement therapy exist, many patients begin
hemodialysis with a dialysis catheter due to logistic and physiologic factors
involved in arteriovenous fistula creation and maturation. Colonization of
catheters via skin flora leads to the production of biofilm, which acts as a
reservoir for virulent bacteria. Preventative therapies center on appropriate
catheter maintenance, infection control measures, and early removal of devices as
patients transition to other access. Despite best efforts, when conservative
measures fail to prevent infections in a high-risk population, antimicrobial lock
therapy should be considered as an option to combat catheter-related bloodstream
infections.