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2016 ; 9
(ä): 236
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Integrating text mining, data mining, and network analysis for identifying
genetic breast cancer trends
#MMPMID27112211
Jurca G
; Addam O
; Aksac A
; Gao S
; Özyer T
; Demetrick D
; Alhajj R
BMC Res Notes
2016[Apr]; 9
(ä): 236
PMID27112211
show ga
BACKGROUND: Breast cancer is a serious disease which affects many women and may
lead to death. It has received considerable attention from the research
community. Thus, biomedical researchers aim to find genetic biomarkers indicative
of the disease. Novel biomarkers can be elucidated from the existing literature.
However, the vast amount of scientific publications on breast cancer make this a
daunting task. This paper presents a framework which investigates existing
literature data for informative discoveries. It integrates text mining and social
network analysis in order to identify new potential biomarkers for breast cancer.
RESULTS: We utilized PubMed for the testing. We investigated gene-gene
interactions, as well as novel interactions such as gene-year, gene-country, and
abstract-country to find out how the discoveries varied over time and how
overlapping/diverse are the discoveries and the interest of various research
groups in different countries. CONCLUSIONS: Interesting trends have been
identified and discussed, e.g., different genes are highlighted in relationship
to different countries though the various genes were found to share
functionality. Some text analysis based results have been validated against
results from other tools that predict gene-gene relations and gene functions.