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10.1080/23723556.2015.1043482

http://scihub22266oqcxt.onion/10.1080/23723556.2015.1043482
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C4845331!4845331!27308560
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suck abstract from ncbi


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pmid27308560      Mol+Cell+Oncol 2016 ; 3 (1): ä
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  • Targeting translesion synthesis to facilitate the eradication of ovarian cancer stem cells by platinum-based therapy #MMPMID27308560
  • Srivastava AK; Wang QE
  • Mol Cell Oncol 2016[Jan]; 3 (1): ä PMID27308560show ga
  • Understanding the mechanisms by which cancer stem cells (CSCs) survive chemotherapy is essential for the development of new therapies. Recently, we demonstrated that ovarian CSCs survive cisplatin treatment through enhanced expression of DNA polymerase ? (Pol ?). Identification of micro RNA-93 (miR-93) as the regulator of Pol ? provides a novel target to improve the outcome of platinum-based therapy.
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