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10.1128/JCM.03394-15

http://scihub22266oqcxt.onion/10.1128/JCM.03394-15
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C4844714!4844714!26865690
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suck abstract from ncbi


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pmid26865690      J+Clin+Microbiol 2016 ; 54 (5): 1191-6
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  • The Past, Present, and (Possible) Future of Serologic Testing for Lyme Disease #MMPMID26865690
  • Theel ES
  • J Clin Microbiol 2016[May]; 54 (5): 1191-6 PMID26865690show ga
  • Lyme disease prevails as the most commonly transmitted tick-borne infection in the United States, and serologic evaluation for antibodies to Borrelia burgdorferi remains the recommended modality for diagnosis. This review presents a brief historical perspective on the evolution of serologic assays for Lyme disease and provides a summary of the performance characteristics for the currently recommended two-tiered testing algorithm (TTTA). Additionally, a recently proposed alternative to the traditional TTTA is discussed, and novel methodologies, including immuno-PCR and metabolic profiling for Lyme disease, are outlined.
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