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2016 ; 11
(5
): 3105-3110
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Computed tomography and magnetic resonance features of intracranial
hemangioendothelioma: A study of 7 cases
#MMPMID27123072
Tian WZ
; Yu XR
; Wang WW
; Zhang BO
; Xia JG
; Liu HQ
Oncol Lett
2016[May]; 11
(5
): 3105-3110
PMID27123072
show ga
The current study aimed to present the neuroradiological and histopathological
features of intracranial hemangioendothelioma (HE). The computed tomography (CT;
n=3) and magnetic resonance imaging (MRI; n=7) features, and the clinical
presentations of 7 patients with pathologically documented HEs were
retrospectively analyzed. Lesions were observed in the right side of the skull
(the frontal bone in 1 patient and the parietal bone in 1 patient), the tentorium
(2 patients), the cerebral falx (1 patient), the right cavernous sinus (1
patient) and the right temporal lobe (1 patient). The tumor was lobulated in 5
cases and round in 2 cases. The majority of tumors appeared isointense or
hypointense with multiple scattered hyperintensities on T1-weighted MRI.
Moreover, the lesions appeared as inhomogeneous hyperintense regions with
multiple enlarged and tortuous blood flow voids on T2-weighted MRI. The lesions
also showed marked gadolinium enhancement in a honeycomb pattern. CT scan results
showed a isoattenuation region (32-47 HU), with numerous small, round,
high-density foci. The 2 cases with skull lesions presented with local bone
destruction and discontinuous bone lines of the tabula interna ossis cranii. In 1
case, MR angiography revealed abnormal vessels in the basilar region. A total of
4 cases were epithelial HE, 2 were retiform HE and 1 was kaposiform HE.
Histological examination revealed endothelial cell proliferation with vascular
lesions and a mucous matrix or dense fibrous mesenchyme. In conclusion,
intracranial HE is rare, but should be considered in the differential diagnosis
when evaluating intracranial neoplasms. A well-defined lobulated mass and imaging
features that include internal heterogeneity, small scattered hemorrhages and
thromboses, signal voids of vessels, and marked and delayed enhancement may
confirm the diagnosis of HE.