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2016 ; 4
(ä): 16
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English Wikipedia
Bacterial communities in penile skin, male urethra, and vaginas of heterosexual
couples with and without bacterial vaginosis
#MMPMID27090518
Zozaya M
; Ferris MJ
; Siren JD
; Lillis R
; Myers L
; Nsuami MJ
; Eren AM
; Brown J
; Taylor CM
; Martin DH
Microbiome
2016[Apr]; 4
(ä): 16
PMID27090518
show ga
BACKGROUND: The epidemiology of bacterial vaginosis (BV) suggests it is sexually
transmissible, yet no transmissible agent has been identified. It is probable
that BV-associated bacterial communities are transferred from male to female
partners during intercourse; however, the microbiota of sexual partners has not
been well-studied. RESULTS: Pyrosequencing analysis of PCR-amplified 16S rDNA was
used to examine BV-associated bacteria in monogamous couples with and without BV
using vaginal, male urethral, and penile skin specimens. The penile skin and
urethral microbiota of male partners of women with BV was significantly more
similar to the vaginal microbiota of their female partner compared to the vaginal
microbiota of non-partner women with BV. This was not the case for male partners
of women with normal vaginal microbiota. Specific BV-associated species were
concordant in women with BV and their male partners. CONCLUSIONS: In monogamous
heterosexual couples in which the woman has BV, the significantly higher
similarity between the vaginal microbiota and the penile skin and urethral
microbiota of the male partner, supports the hypothesis that sexual exchange of
BV-associated bacterial taxa is common.