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10.1016/j.urolonc.2016.01.006 http://scihub22266oqcxt.onion/10.1016/j.urolonc.2016.01.006 C4834698!4834698!26923782     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Urol+Oncol 2016 ; 34 (4): 171-81 Nephropedia Template TP {{tp|p=26923782|t=2016. Blocking Immune Checkpoints in Prostate, Kidney and Urothelial cancer: An Overview |pdf=|usr=}}{{26923782}} gab.com Text Blocking Immune Checkpoints in Prostate, Kidney and Urothelial cancer: An Overview JO: Urol Oncol http://www.kidney.de/pget.php?&tw=1&pmid=26923782 #FOAvip Despite a long history of immunotherapeutic approaches to treatment, most genitourinary malignancies are not cured by existing immunotherapy regimens. More recently, cell-surface molecules known as immune checkpoints have become the focus of efforts to develop more effective immunotherapies. Interactions between these molecules and their ligands inhibit the proliferation and function of tumor-specific lymphocytes. A monoclonal antibody blocking one of these checkpoints was approved for the treatment of metastatic melanoma and is now being tested in other malignancies. The objective responses seen in these early trials of checkpoint blockade are driving renewed enthusiasm for cancer immunotherapy. There are several ongoing and planned trials in genitourinary malignancies of single-agent inhibitors, as well as combinations targeting multiple checkpoints or adding other types of therapies to checkpoint blockade. Twit Text FOAVip Blocking Immune Checkpoints in Prostate, Kidney and Urothelial cancer: An Overview ????Urol Oncol http://www.kidney.de/pget.php?&tw=1&pmid=26923782 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26923782 #FOAvip English Wikipedia <ref>{{Cite pmid|26923782}}</ref> Blocking Immune Checkpoints in Prostate, Kidney and Urothelial cancer: An Overview #MMPMID26923782 Alme AK; Karir BS; Faltas BM; Drake CG Urol Oncol 2016[Apr]; 34 (4): 171-81 PMID26923782show ga Despite a long history of immunotherapeutic approaches to treatment, most genitourinary malignancies are not cured by existing immunotherapy regimens. More recently, cell-surface molecules known as immune checkpoints have become the focus of efforts to develop more effective immunotherapies. Interactions between these molecules and their ligands inhibit the proliferation and function of tumor-specific lymphocytes. A monoclonal antibody blocking one of these checkpoints was approved for the treatment of metastatic melanoma and is now being tested in other malignancies. The objective responses seen in these early trials of checkpoint blockade are driving renewed enthusiasm for cancer immunotherapy. There are several ongoing and planned trials in genitourinary malignancies of single-agent inhibitors, as well as combinations targeting multiple checkpoints or adding other types of therapies to checkpoint blockade. äBlocking Immune Checkpoints in Prostate, Kidney and Urothelial cancer:(epmc).pdf DeepDyve Pubget Overpricing