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10.1002/1873-3468.12061 http://scihub22266oqcxt.onion/10.1002/1873-3468.12061 C4833664!4833664!26780878     free     free     free       FEBS+Lett 2016 ; 590 (7): 924-34 Nephropedia Template TP {{tp|p=26780878|t=2016. p53 as guardian of the mitochondrial genome |pdf=|usr=}}{{26780878}} gab.com Text p53 as guardian of the mitochondrial genome JO: FEBS Lett http://www.kidney.de/pget.php?&tw=1&pmid=26780878 #FOAvip Participating in the repair of nuclear DNA is one mechanism by which p53 suppresses tumorigenesis, but there is growing evidence that p53 also helps maintain the mitochondrial genome through its translocation into mitochondria and interactions with mtDNA repair proteins. Because of the susceptibility of mtDNA to oxidative damage and replication errors, it is vital to protect mtDNA genomic stability to preserve health and fitness. Here, we focus on reviewing the evidence for the involvement of p53 in maintaining the integrity of mtDNA through its activities in both the nucleus and the mitochondria. Twit Text FOAVip p53 as guardian of the mitochondrial genome ????FEBS Lett http://www.kidney.de/pget.php?&tw=1&pmid=26780878 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26780878 #FOAvip English Wikipedia <ref>{{Cite pmid|26780878}}</ref> p53 as guardian of the mitochondrial genome #MMPMID26780878 Park JH; Zhuang J; Li J; Hwang PM FEBS Lett 2016[Apr]; 590 (7): 924-34 PMID26780878show ga Participating in the repair of nuclear DNA is one mechanism by which p53 suppresses tumorigenesis, but there is growing evidence that p53 also helps maintain the mitochondrial genome through its translocation into mitochondria and interactions with mtDNA repair proteins. Because of the susceptibility of mtDNA to oxidative damage and replication errors, it is vital to protect mtDNA genomic stability to preserve health and fitness. Here, we focus on reviewing the evidence for the involvement of p53 in maintaining the integrity of mtDNA through its activities in both the nucleus and the mitochondria. äp53 as guardian of the mitochondrial genome (epmc).pdf DeepDyve Pubget Overpricing