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10.1002/1873-3468.12121 http://scihub22266oqcxt.onion/10.1002/1873-3468.12121 C4833639!4833639!26938658     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       FEBS+Lett 2016 ; 590 (7): 885-907 Nephropedia Template TP {{tp|p=26938658|t=2016. Attacking the supply wagons to starve cancer cells to death |pdf=|usr=}}{{26938658}} gab.com Text Attacking the supply wagons to starve cancer cells to death JO: FEBS Lett http://www.kidney.de/pget.php?&tw=1&pmid=26938658 #FOAvip The constitutive anabolism of cancer cells supports proliferation but also addicts tumor cells to a steady influx of exogenous nutrients. Limiting access to metabolic substrates could be an effective and selective means to block cancer growth. In this review, we define the pathways by which cancer cells acquire the raw materials for anabolism, highlight the actionable proteins in each pathway, and discuss the status of therapeutic interventions that disrupt nutrient acquisition. Critical open questions to be answered before apical metabolic inhibitors can be successfully and safely deployed in the clinic are also outlined. In summary, recent studies provide strong support that substrate limitation is a powerful therapeutic strategy to effectively, and safely, starve cancer cells to death. Twit Text FOAVip Attacking the supply wagons to starve cancer cells to death ????FEBS Lett http://www.kidney.de/pget.php?&tw=1&pmid=26938658 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26938658 #FOAvip English Wikipedia <ref>{{Cite pmid|26938658}}</ref> Attacking the supply wagons to starve cancer cells to death #MMPMID26938658 Selwan E; Finicle BT; Kim SM; Edinger AL FEBS Lett 2016[Apr]; 590 (7): 885-907 PMID26938658show ga The constitutive anabolism of cancer cells supports proliferation but also addicts tumor cells to a steady influx of exogenous nutrients. Limiting access to metabolic substrates could be an effective and selective means to block cancer growth. In this review, we define the pathways by which cancer cells acquire the raw materials for anabolism, highlight the actionable proteins in each pathway, and discuss the status of therapeutic interventions that disrupt nutrient acquisition. Critical open questions to be answered before apical metabolic inhibitors can be successfully and safely deployed in the clinic are also outlined. In summary, recent studies provide strong support that substrate limitation is a powerful therapeutic strategy to effectively, and safely, starve cancer cells to death. äAttacking the supply wagons to starve cancer cells to death (epmc).pdf DeepDyve Pubget Overpricing