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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Biol+Blood+Marrow+Transplant
2015 ; 21
(11
): 1863-1869
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Indications for Autologous and Allogeneic Hematopoietic Cell Transplantation:
Guidelines from the American Society for Blood and Marrow Transplantation
#MMPMID26256941
Majhail NS
; Farnia SH
; Carpenter PA
; Champlin RE
; Crawford S
; Marks DI
; Omel JL
; Orchard PJ
; Palmer J
; Saber W
; Savani BN
; Veys PA
; Bredeson CN
; Giralt SA
; LeMaistre CF
Biol Blood Marrow Transplant
2015[Nov]; 21
(11
): 1863-1869
PMID26256941
show ga
Approximately 20,000 hematopoietic cell transplantation (HCT) procedures are
performed in the United States annually. With advances in transplantation
technology and supportive care practices, HCT has become safer, and patient
survival continues to improve over time. Indications for HCT continue to evolve
as research refines the role for HCT in established indications and identifies
emerging indications where HCT may be beneficial. The American Society for Blood
and Marrow Transplantation (ASBMT) established a multiple-stakeholder task force
consisting of transplant experts, payer representatives, and a patient advocate
to provide guidance on "routine" indications for HCT. This white paper presents
the recommendations from the task force. Indications for HCT were categorized as
follows: (1) Standard of care, where indication for HCT is well defined and
supported by evidence; (2) Standard of care, clinical evidence available, where
large clinical trials and observational studies are not available but HCT has
been shown to be effective therapy; (3) Standard of care, rare indication, for
rare diseases where HCT has demonstrated effectiveness but large clinical trials
and observational studies are not feasible; (4) Developmental, for diseases where
preclinical and/or early phase clinical studies show HCT to be a promising
treatment option; and (5) Not generally recommended, where available evidence
does not support the routine use of HCT. The ASBMT will periodically review these
guidelines and will update them as new evidence becomes available.