Roles of Circular RNAs in Neurologic Disease #MMPMID27147959
Shao Y; Chen Y
Front Mol Neurosci 2016[]; 9 (ä): ä PMID27147959show ga
Circular RNAs (circRNAs) are a novel type of endogenous noncoding RNA receiving increasing attention. They have been shown to act as a natural microRNA sponges that repress the activity of corresponding miRNAs by binding with them, thus regulating target genes. Numerous studies have shown that miRNAs are involved in the pathogenesis of neurological diseases. Therefore, circRNAs may act as important regulatory factors in the occurrence and development processes of neurological disease.