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10.1080/15476286.2015.1094601

http://scihub22266oqcxt.onion/10.1080/15476286.2015.1094601
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C4829328!4829328!26400469
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suck abstract from ncbi


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pmid26400469      RNA+Biol 2015 ; 12 (11): 1178-80
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  • miRNA-encoded peptides (miPEPs): A new tool to analyze the roles of miRNAs in plant biology #MMPMID26400469
  • Couzigou JM; Lauressergues D; Bécard G; Combier JP
  • RNA Biol 2015[Nov]; 12 (11): 1178-80 PMID26400469show ga
  • MicroRNAs (miRNAs) are short RNA molecules negatively regulating the expression of many important genes in plants and animals. We have recently shown that plant primary transcripts of miRNAs encode peptides (miPEPs) able to increase specifically the transcription of their associated miRNA.1 We discuss here the possibility of using miPEPs as a new tool for functional analysis of single members of miRNA families in plants, including in non-model plants, that could avoid transgenic transformation and minimize artifactual interpretation. We also raise several fundamental and crucial questions that need to be address for a deeper understanding of the cellular and molecular mechanisms underlining the regulatory activity of miPEPs.
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