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2016 ; 28
(2
): 210-5
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The Importance of Collagen Tissue in Papular Elastorrhexis, Eruptive Collagenoma,
and Nevus Anelasticus
#MMPMID27081269
Lee SH
; Sung NH
Ann Dermatol
2016[Apr]; 28
(2
): 210-5
PMID27081269
show ga
BACKGROUND: Papular elastorrhexis (PE), eruptive collagenoma (EC), and nevus
anelasticus (NA) are described as multiple small papules with decrease,
fragmentation, or lack of dermal elastic fibers. These diseases are suggested to
be the same entity. The change of collagen fibers in the conditions has not been
addressed to date. OBJECTIVE: We compared the clinical features of the 3 diseases
and investigated changes in the collagen fibers involved. METHODS: Twenty-four
cases of PE, 12 cases of EC, and 2 cases of NA found in PubMed and the Korean
database were reviewed. Changes in dermal collagen fibers in 10 cases with
histological figures were investigated. RESULTS: There were significant
similarities between the 3 entities in terms of their clinical features. Four
patients with PE and 2 with EC with fine, dense collagen fibers were women who
had multiple white to hypopigmented, slightly indurated to firm, millimeter-size
papules on the trunk and/or extremities that progressed gradually after
developing in the patients' first to third decades. CONCLUSION: The 3 conditions
are the same clinical entity in our opinion; such cases with fine, dense collagen
manifest typical features.