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2016 ; 9
(ä): 81-6
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The effect of ONCE Renal on minerals and electrolytes in predialysis patients
with chronic kidney disease
#MMPMID27103839
Satirapoj B
; Prapakorn J
; Punpanich D
; Pongsuparbchon C
; Supasyndh O
Int J Nephrol Renovasc Dis
2016[]; 9
(ä): 81-6
PMID27103839
show ga
BACKGROUND: Malnutrition is one common adverse consequence in patients with
advanced chronic kidney disease (CKD), and most patients have a lower-than-normal
dietary energy intake. The present study was undertaken to examine whether orally
administered ONCE Renal formula (ORF) supplement would improve energy intake
without minerals and electrolytes disturbances in predialysis patients with CKD.
METHODS: All eligible nondiabetic patients with CKD received ORF supplement for 1
week. Nutrition markers, renal function, and minerals and electrolytes were
evaluated before and after supplementing. All patients kept a 3-day food record
and were interviewed by a registered dietitian. RESULTS: A total of 29 patients
with mean age 64.9±13.3 years were included. Mean estimated glomerular filtration
rate was 37.7±12.1 mL/min/1.73 m(2). A significant increase was observed in
amount of energy, fat, fiber, calcium, and magnesium intake after 1 week of ORF
supplement. Moreover, in comparison with baseline values, the patients displayed
decreased dietary protein intake and blood urea nitrogen and increased serum
magnesium. However, no significant change was found in renal function,
nutritional markers (body weight, prealbumin, albumin, and protein equivalence of
total nitrogen appearance), serum calcium, phosphorus, sodium, potassium, and
bicarbonate. CONCLUSION: In patients with CKD, ingestion of ORF was well
tolerated and had a positive effect with an increase in dietary energy, fat, and
fiber intake, as well as a decreased dietary protein intake. No mineral or
electrolyte abnormalities were observed during the study.