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10.2147/OTT.S96899 http://scihub22266oqcxt.onion/10.2147/OTT.S96899 C4827894!4827894 !27103826     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=27103826 &cmd=llinks): Failed to open stream: HTTP request failed! 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Mechanism-based management for mucositis: option for treating side effects without compromising the efficacy of cancer therapy |pdf=|usr=}}{{27103826 }} gab.com Text Mechanism-based management for mucositis: option for treating side effects without compromising the efficacy of cancer therapy JO: Onco Targets Ther http://www.kidney.de/pget.php?&tw=1&pmid=27103826 #FOAvip Mucositis is a major side effect induced by chemotherapy and radiotherapy. Although mucositis is a leading cause of morbidity and mortality in cancer patients, management is largely limited to controlling symptoms, and few therapeutic agents are available for treatment. Since mucositis could be inhibited by the modulation of radiotherapy- or chemotherapy-induced pathways independently of cancer treatment, there is an opportunity for the development of more targeted therapies and interventions. This article examined potential therapeutic agents that have been investigated for the prevention and/or inhibition of mucositis induced by conventional chemotherapy and radiotherapy. They can be classified according to their mechanisms of action: scavenging reactive oxygen species, inhibition of specific cytokine production or inflammation, and inhibition of apoptosis. These early events may be good target pathways for preventing the pathogenesis of mucositis. Considering that both cancer therapy and therapeutic agents for mucositis act on both normal and cancer cells, agents that inhibit mucositis should act through mechanisms that selectively protect normal cells without compromising cancer treatment. Therefore, mechanism-based guidance for the treatment of mucositis is critical to prevent risky treatments for cancer patients and to relieve detrimental side effects effectively from cancer therapy. Twit Text FOAVip Mechanism-based management for mucositis: option for treating side effects without compromising the efficacy of cancer therapy ????Onco Targets Ther http://www.kidney.de/pget.php?&tw=1&pmid=27103826 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27103826 #FOAvip English Wikipedia <ref>{{Cite pmid|27103826 }}</ref> Mechanism-based management for mucositis: option for treating side effects without compromising the efficacy of cancer therapy #MMPMID27103826 Kwon Y Onco Targets Ther 2016[]; 9 (ä): 2007-16 PMID27103826 show ga Mucositis is a major side effect induced by chemotherapy and radiotherapy. Although mucositis is a leading cause of morbidity and mortality in cancer patients, management is largely limited to controlling symptoms, and few therapeutic agents are available for treatment. Since mucositis could be inhibited by the modulation of radiotherapy- or chemotherapy-induced pathways independently of cancer treatment, there is an opportunity for the development of more targeted therapies and interventions. This article examined potential therapeutic agents that have been investigated for the prevention and/or inhibition of mucositis induced by conventional chemotherapy and radiotherapy. They can be classified according to their mechanisms of action: scavenging reactive oxygen species, inhibition of specific cytokine production or inflammation, and inhibition of apoptosis. These early events may be good target pathways for preventing the pathogenesis of mucositis. Considering that both cancer therapy and therapeutic agents for mucositis act on both normal and cancer cells, agents that inhibit mucositis should act through mechanisms that selectively protect normal cells without compromising cancer treatment. Therefore, mechanism-based guidance for the treatment of mucositis is critical to prevent risky treatments for cancer patients and to relieve detrimental side effects effectively from cancer therapy. äMechanism-based management for mucositis: option for treating side eff(epmc).pdf DeepDyve Pubget Overpricing