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10.12688/f1000research.7537.1

http://scihub22266oqcxt.onion/10.12688/f1000research.7537.1
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C4821294!4821294 !27092250
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suck abstract from ncbi

pmid27092250
      F1000Res 2016 ; 5 (?): ?
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  • The emerging role of phosphoinositide clustering in intracellular trafficking and signal transduction #MMPMID27092250
  • Picas L ; Gaits-Iacovoni F ; Goud B
  • F1000Res 2016[]; 5 (?): ? PMID27092250 show ga
  • Phosphoinositides are master regulators of multiple cellular processes: from vesicular trafficking to signaling, cytoskeleton dynamics, and cell growth. They are synthesized by the spatiotemporal regulated activity of phosphoinositide-metabolizing enzymes. The recent observation that some protein modules are able to cluster phosphoinositides suggests that alternative or complementary mechanisms might operate to stabilize the different phosphoinositide pools within cellular compartments. Herein, we discuss the different known and potential molecular players that are prone to engage phosphoinositide clustering and elaborate on how such a mechanism might take part in the regulation of intracellular trafficking and signal transduction.
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