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2015 ; 3
(ä): 2050312115613351
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Assessment of the interstitial fluid in the subcutaneous tissue of healthy adults
using ultrasonography
#MMPMID27092255
Ueda-Iuchi T
; Ohno N
; Miyati T
; Dai M
; Okuwa M
; Nakatani T
; Sanada H
; Sugama J
SAGE Open Med
2015[]; 3
(ä): 2050312115613351
PMID27092255
show ga
OBJECTIVE: Lymphoedema involves swelling, especially in the subcutaneous tissues.
For lymphoedema management to be successful, it is necessary to remove the
interstitial fluid. Subcutaneous echogenicity may be associated with interstitial
fluid, but echogenicity is not an indicator for the evaluation of management
because we do not directly compare echogenicity with the interstitial fluid. We
aimed to identify an outcome indicator for the evaluation of interstitial fluid
using ultrasonography. We assessed the correlation between echogenicity and
transverse relaxation rate (R2) on magnetic resonance imaging. METHODS: This was
an observational study. Healthy adults with leg swelling after activity for >8?h
were recruited. The legs of 13 women were evaluated using ultrasonography,
magnetic resonance imaging and measurements of the limb circumference before and
after an intervention to reduce the swelling. RESULTS: Echogenicity in the oedema
group was greater than that of the controls. Echogenicity decreased with
reductions in oedema. The range of the strongest correlations with the changes in
R2 occurred at echogenicity values of 48-144 (Pearson's correlation coefficient:
r?=?-0.63 and p?0.01). Thus, it was possible to evaluate the interstitial fluid
using echogenicity. CONCLUSION: The outcome indicators for the evaluation of
interstitial fluid using ultrasonography were echogenicities in the range of
48-144, and these values were valid for assessing the interstitial fluid in the
subcutaneous tissue.