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2016 ; 30
(2
): 92-100
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English Wikipedia
Factors Affecting Long-term Myopic Regression after Laser In Situ Keratomileusis
and Laser-assisted Subepithelial Keratectomy for Moderate Myopia
#MMPMID27051256
Lim SA
; Park Y
; Cheong YJ
; Na KS
; Joo CK
Korean J Ophthalmol
2016[Apr]; 30
(2
): 92-100
PMID27051256
show ga
PURPOSE: High myopia is known to be a risk factor for long-term regression after
laser refractive surgery. There have been few studies about the correction of
moderate myopias that did not need retreatment after long-term follow-up. We
evaluated 10 years of change in visual acuity and refractive power in eyes with
moderate myopia after laser refractive surgery. METHODS: We included patients
that had undergone laser in situ keratomileusis (LASIK) or laser-assisted
subepithelial keratectomy (LASEK) to correct their myopia and that had at least
10 years of follow-up. We evaluated the stability of visual acuity in terms of
safety, efficacy, and refractive changes at examinations 6 months and 1, 2, 5, 7,
and 10 years after surgery. RESULTS: The study evaluated 62 eyes (36 eyes in
LASIK patients and 26 eyes in LASEK patients). In both groups, the efficacy index
tended to decrease, and it was consistently higher in the LASEK group compared to
the LASIK group over the 10 years of follow-up. The safety index improved over 10
years and was always higher than 0.9 in both groups. The difference between the
spherical equivalent at 6 months postoperatively and later periods was
statistically significant after 5, 7, and 10 years in both groups (LASIK, p =
0.036, p = 0.003, and p < 0.001, respectively; LASEK, p = 0.006, p = 0.002, and p
= 0.001, respectively). Ten years after surgery,26 eyes (66.7%) in the LASIK
group and 19 eyes (73.1%) in the LASEK group had myopia greater than 1 diopter.
In comparison with the thickness at 6 months postoperatively, central corneal
thickness was significantly increased after 5, 7, and 10 years in both LASIK and
LASEK groups (LASIK, p < 0.001, p < 0.001, and p < 0.001, respectively; LASEK, p
= 0.01, p < 0.001, and p < 0.001, respectively). CONCLUSIONS: Moderately myopic
eyes showed progressive myopic shifting and corneal thickening after LASIK and
LASEK during 10 years of follow-up. We also found that early refractive
regression may indicate the long-term refractive outcome.