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10.1093/jmcb/mjw012

http://scihub22266oqcxt.onion/10.1093/jmcb/mjw012
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C4816149!4816149!26993045
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suck abstract from ncbi

pmid26993045      J+Mol+Cell+Biol 2016 ; 8 (2): 120-8
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  • Adiponectin: a versatile player of innate immunity #MMPMID26993045
  • Luo Y; Liu M
  • J Mol Cell Biol 2016[Apr]; 8 (2): 120-8 PMID26993045show ga
  • Adiponectin acts as a key regulator of the innate immune system and plays a major role in the progression of inflammation and metabolic disorders. Macrophages and monocytes are representative components of the innate immune system, and their proliferation, plasticity, and polarization are a key component of metabolic adaption. Innate-like lymphocytes such as group 2 innate lymphoid cells (ILC2s), natural killer T (NKT) cells, and gamma delta T (?? T) cells are also members of the innate immune system and play important roles in the development of obesity and its related diseases. Adiponectin senses metabolic stress and modulates metabolic adaption by targeting the innate immune system under physiological and pathological conditions. Defining the mechanisms underlying the role of adiponectin in regulating innate immunity is crucial to adiponectin-based therapeutic intervention.
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