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10.1186/s13059-016-0909-0 http://scihub22266oqcxt.onion/10.1186/s13059-016-0909-0 C4815170!4815170 !27036497     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\27036497 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Genome+Biol 2016 ; 17 (ä): 59 Nephropedia Template TP {{tp|p=27036497 |t=2016. Predicting the three-dimensional folding of cis-regulatory regions in mammalian genomes using bioinformatic data and polymer models |pdf=|usr=}}{{27036497 }} gab.com Text Predicting the three-dimensional folding of cis-regulatory regions in mammalian genomes using bioinformatic data and polymer models JO: Genome Biol http://www.kidney.de/pget.php?&tw=1&pmid=27036497 #FOAvip The three-dimensional (3D) organization of chromosomes can be probed using methods like Capture-C. However, it is unclear how such population-level data relate to the organization within a single cell, and the mechanisms leading to the observed interactions are still largely obscure. We present a polymer modeling scheme based on the assumption that chromosome architecture is maintained by protein bridges, which form chromatin loops. To test the model, we perform FISH experiments and compare with Capture-C data. Starting merely from the locations of protein binding sites, our model accurately predicts the experimentally observed chromatin interactions, revealing a population of 3D conformations. Twit Text FOAVip Predicting the three-dimensional folding of cis-regulatory regions in mammalian genomes using bioinformatic data and polymer models ????Genome Biol http://www.kidney.de/pget.php?&tw=1&pmid=27036497 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27036497 #FOAvip English Wikipedia <ref>{{Cite pmid|27036497 }}</ref> Predicting the three-dimensional folding of cis-regulatory regions in mammalian genomes using bioinformatic data and polymer models #MMPMID27036497 Brackley CA ; Brown JM ; Waithe D ; Babbs C ; Davies J ; Hughes JR ; Buckle VJ ; Marenduzzo D Genome Biol 2016[Mar]; 17 (ä): 59 PMID27036497 show ga The three-dimensional (3D) organization of chromosomes can be probed using methods like Capture-C. However, it is unclear how such population-level data relate to the organization within a single cell, and the mechanisms leading to the observed interactions are still largely obscure. We present a polymer modeling scheme based on the assumption that chromosome architecture is maintained by protein bridges, which form chromatin loops. To test the model, we perform FISH experiments and compare with Capture-C data. Starting merely from the locations of protein binding sites, our model accurately predicts the experimentally observed chromatin interactions, revealing a population of 3D conformations. |*Regulatory Sequences, Nucleic Acid [MESH] |Animals [MESH] |Chromosomes, Mammalian/*chemistry/genetics/metabolism [MESH] |Computational Biology/*methods [MESH] |Humans [MESH] |In Situ Hybridization, Fluorescence [MESH] |Mice [MESH] |Models, Biological [MESH] |Models, Molecular [MESH] |Nucleic Acid Conformation [MESH]Predicting the three-dimensional folding of cis-regulatory regions in (epmc).pdf DeepDyve Pubget Overpricing