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10.1111/imr.12155 http://scihub22266oqcxt.onion/10.1111/imr.12155 C4813657!4813657!24517433     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Immunol+Rev 2014 ; 258 (1): 167-82 Nephropedia Template TP {{tp|p=24517433|t=2014. Recollective Homeostasis and the Immune Consequences of Peritransplant Depletional Induction Therapy |pdf=|usr=}}{{24517433}} gab.com Text Recollective Homeostasis and the Immune Consequences of Peritransplant Depletional Induction Therapy JO: Immunol Rev http://www.kidney.de/pget.php?&tw=1&pmid=24517433 #FOAvip Ones cellular immune repertoire is composed of lymphocytes in multiple stages of maturation?the dynamic product of their responses to antigenic challenges and the homeostatic contractions necessary to accommodate immune expansions within physiologic norms. Given that alloreactivity is predominantly a cross-reactive phenomenon that is stochastically distributed throughout the overall T cell repertoire, ones allospecific repertoire is similarly made up of cells in a variety of differentiation states. As such, the continuous expansion and elimination of activated memory populations, producing a ?recollective homeostasis? of sorts, has the potential over time to alter the maturation state and effector composition of both ones protective and alloreactive T cell repertoire. Importantly, a T cell?s maturation state significantly influences its response to numerous immunomodulatory therapies used in organ transplantation, including depletional antibody induction. In this review, we discuss clinically utilized depletional induction strategies, how their use alters a transplant recipient?s cellular immune repertoire, and how a recipient?s repertoire influences the clinical effects of induction therapy. Twit Text FOAVip Recollective Homeostasis and the Immune Consequences of Peritransplant Depletional Induction Therapy ????Immunol Rev http://www.kidney.de/pget.php?&tw=1&pmid=24517433 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24517433 #FOAvip English Wikipedia <ref>{{Cite pmid|24517433}}</ref> Recollective Homeostasis and the Immune Consequences of Peritransplant Depletional Induction Therapy #MMPMID24517433 Rosenblum JM; Kirk AD Immunol Rev 2014[Mar]; 258 (1): 167-82 PMID24517433show ga Ones cellular immune repertoire is composed of lymphocytes in multiple stages of maturation?the dynamic product of their responses to antigenic challenges and the homeostatic contractions necessary to accommodate immune expansions within physiologic norms. Given that alloreactivity is predominantly a cross-reactive phenomenon that is stochastically distributed throughout the overall T cell repertoire, ones allospecific repertoire is similarly made up of cells in a variety of differentiation states. As such, the continuous expansion and elimination of activated memory populations, producing a ?recollective homeostasis? of sorts, has the potential over time to alter the maturation state and effector composition of both ones protective and alloreactive T cell repertoire. Importantly, a T cell?s maturation state significantly influences its response to numerous immunomodulatory therapies used in organ transplantation, including depletional antibody induction. In this review, we discuss clinically utilized depletional induction strategies, how their use alters a transplant recipient?s cellular immune repertoire, and how a recipient?s repertoire influences the clinical effects of induction therapy. äRecollective Homeostasis and the Immune Consequences of Peritransplant(epmc).pdf DeepDyve Pubget Overpricing