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10.3390/ijms17030332

http://scihub22266oqcxt.onion/10.3390/ijms17030332
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suck abstract from ncbi


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pmid26950124
      Int+J+Mol+Sci 2016 ; 17 (3 ): 332
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  • Crosstalk between Autophagy and Apoptosis: Potential and Emerging Therapeutic Targets for Cardiac Diseases #MMPMID26950124
  • Li M ; Gao P ; Zhang J
  • Int J Mol Sci 2016[Mar]; 17 (3 ): 332 PMID26950124 show ga
  • Autophagy is a cell survival process which is related to breaking down and reusing cytoplasm components. Moreover, autophagy regulates cell death under certain conditions. Apoptosis has the characteristics of chromatin agglutination and the shrinking of nuclear and apoptosis body form. Even if the mechanisms of autophagy and apoptosis have differences, some proteins modulate both autophagy and apoptosis. Crosstalk between them exists. This review highlights recent advances in the interaction of autophagy and apoptosis and its importance in the development of cardiovascular diseases.
  • |*Apoptosis/drug effects [MESH]
  • |*Autophagy/drug effects [MESH]
  • |*Signal Transduction/drug effects [MESH]
  • |Animals [MESH]
  • |Autophagy-Related Proteins/metabolism [MESH]
  • |Beclin-1/metabolism [MESH]
  • |Cardiovascular Diseases/drug therapy/*metabolism/pathology [MESH]
  • |Cardiovascular System/drug effects/*metabolism/pathology [MESH]
  • |Caspases/metabolism [MESH]
  • |Humans [MESH]
  • |Molecular Targeted Therapy [MESH]
  • |Proto-Oncogene Proteins c-bcl-2/metabolism [MESH]


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