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10.1007/s12195-015-0420-9 http://scihub22266oqcxt.onion/10.1007/s12195-015-0420-9 C4812444!4812444!27042237     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Cell+Mol+Bioeng 2016 ; 9 (1): 85-95 Nephropedia Template TP {{tp|p=27042237|t=2016. Effect of Pseudopod Extensions on Neutrophil Hemodynamic Transport Near a Wall |pdf=|usr=}}{{27042237}} gab.com Text Effect of Pseudopod Extensions on Neutrophil Hemodynamic Transport Near a Wall JO: Cell Mol Bioeng http://www.kidney.de/pget.php?&tw=1&pmid=27042237 #FOAvip During inflammation, circulating neutrophils roll on, and eventually tether to, the endothelial lining of blood vessels, allowing them to exit the bloodstream and enter the surrounding tissue to target pathogens. This process is mediated by the selectin family of adhesion proteins expressed by endothelial cells. Interestingly, only 10% of activated, migrating neutrophils transmigrate into the extravascular space; the other 90% detach from the wall and rejoin the blood flow. Neutrophils extrude pseudopods during the adhesion cascade; however, the transport behavior of this unique cell geometry has not been previously addressed. In this study, a three-dimensional computational model was applied to neutrophils with pseudopodial extensions to study the effect of cell shape on the hydrodynamic transport of neutrophils. The collision time, contact area, contact force, and collision frequency were analyzed as a function of pseudopod length. It was found that neutrophils experience more frequent collisions compared to prolate spheroids of equal volume and length. Longer pseudopods and lower shear rates increase the collision time integral contact area, a predictor of binding potential. Our results indicate that contact between the neutrophil and the vessel wall was found to be focused predominantly on the pseudopod tip. Twit Text FOAVip Effect of Pseudopod Extensions on Neutrophil Hemodynamic Transport Near a Wall ????Cell Mol Bioeng http://www.kidney.de/pget.php?&tw=1&pmid=27042237 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27042237 #FOAvip English Wikipedia <ref>{{Cite pmid|27042237}}</ref> Effect of Pseudopod Extensions on Neutrophil Hemodynamic Transport Near a Wall #MMPMID27042237 Rocheleau AD; Wang W; King MR Cell Mol Bioeng 2016[Mar]; 9 (1): 85-95 PMID27042237show ga During inflammation, circulating neutrophils roll on, and eventually tether to, the endothelial lining of blood vessels, allowing them to exit the bloodstream and enter the surrounding tissue to target pathogens. This process is mediated by the selectin family of adhesion proteins expressed by endothelial cells. Interestingly, only 10% of activated, migrating neutrophils transmigrate into the extravascular space; the other 90% detach from the wall and rejoin the blood flow. Neutrophils extrude pseudopods during the adhesion cascade; however, the transport behavior of this unique cell geometry has not been previously addressed. In this study, a three-dimensional computational model was applied to neutrophils with pseudopodial extensions to study the effect of cell shape on the hydrodynamic transport of neutrophils. The collision time, contact area, contact force, and collision frequency were analyzed as a function of pseudopod length. It was found that neutrophils experience more frequent collisions compared to prolate spheroids of equal volume and length. Longer pseudopods and lower shear rates increase the collision time integral contact area, a predictor of binding potential. Our results indicate that contact between the neutrophil and the vessel wall was found to be focused predominantly on the pseudopod tip. äEffect of Pseudopod Extensions on Neutrophil Hemodynamic Transport Nea(epmc).pdf DeepDyve Pubget Overpricing