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2016 ; 7
(2
): e00169
Nephropedia Template TP
gab.com Text
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Kisameet Clay Isolated from the Central Coast of British Columbia, Canada,
Demonstrates Broad-Spectrum Antimicrobial Activity
#MMPMID26956585
Zhanel GG
; Karlowsky JA
mBio
2016[Mar]; 7
(2
): e00169
PMID26956585
show ga
Clay minerals are naturally occurring layered phyllosilicates which consist of
fine particles and possess antimicrobial activity. In a recent article,
Behroozian et al. obtained Kisameet clay (KC) from Kisameet, from the central
coast of British Columbia, Canada, northwest of Vancouver and assessed its
antimicrobial activity versus 16 selected ESKAPE pathogens (Enterococcus faecium,
Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii,
Pseudomonas aeruginosa, and Enterobacter spp.) possessing a variety of different
resistance profiles [S. Behroozian, S. L. Svensson, and J. Davies, mBio
7(1):e01842-15, 2016, http://dx.doi.org/10.1128/mBio.01842-15]. KC demonstrated
complete bacterial eradication of Klebsiella pneumoniae, Acinetobacter baumannii,
Pseudomonas aeruginosa, and Staphylococcus aureus within 24 h. For Enterobacter
spp., the organisms were eradicated with 1% KC within 5 h, while for Enterococcus
faecium, it took 48 h to kill all organisms. Although many questions need to be
answered, these exciting findings highlight the importance of testing natural
substances/products from around the globe to assess whether they possess
antimicrobial activity and potential for usage as topical, oral, or systemic
agents for the treatment of multidrug-resistant pathogens.