Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1128/MCB.00758-15 http://scihub22266oqcxt.onion/10.1128/MCB.00758-15 C4810463!4810463!26729464     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Mol+Cell+Biol 2016 ; 36 (6): 954-64 Nephropedia Template TP {{tp|p=26729464|t=2016. Claudin-21 Has a Paracellular Channel Role at Tight Junctions |pdf=|usr=}}{{26729464}} gab.com Text Claudin-21 Has a Paracellular Channel Role at Tight Junctions JO: Mol Cell Biol http://www.kidney.de/pget.php?&tw=1&pmid=26729464 #FOAvip Claudin protein family members, of which there are at least 27 in humans and mice, polymerize to form tight junctions (TJs) between epithelial cells, in a tissue- and developmental stage-specific manner. Claudins have a paracellular barrier function. In addition, certain claudins function as paracellular channels for small ions and/or solutes by forming selective pores at the TJs, although the specific claudins involved and their functional mechanisms are still in question. Here we show for the first time that claudin-21, which is more highly expressed in the embryonic than the postnatal stages, acts as a paracellular channel for small cations, such as Na+, similar to the typical channel-type claudins claudin-2 and -15. Claudin-21 also allows the paracellular passage of larger solutes. Our findings suggest that claudin-21-based TJs allow the passage of small and larger solutes by both paracellular channel-based and some additional mechanisms. Twit Text FOAVip Claudin-21 Has a Paracellular Channel Role at Tight Junctions ????Mol Cell Biol http://www.kidney.de/pget.php?&tw=1&pmid=26729464 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26729464 #FOAvip English Wikipedia <ref>{{Cite pmid|26729464}}</ref> Claudin-21 Has a Paracellular Channel Role at Tight Junctions #MMPMID26729464 Tanaka H; Yamamoto Y; Kashihara H; Yamazaki Y; Tani K; Fujiyoshi Y; Mineta K; Takeuchi K; Tamura A; Tsukita S Mol Cell Biol 2016[Mar]; 36 (6): 954-64 PMID26729464show ga Claudin protein family members, of which there are at least 27 in humans and mice, polymerize to form tight junctions (TJs) between epithelial cells, in a tissue- and developmental stage-specific manner. Claudins have a paracellular barrier function. In addition, certain claudins function as paracellular channels for small ions and/or solutes by forming selective pores at the TJs, although the specific claudins involved and their functional mechanisms are still in question. Here we show for the first time that claudin-21, which is more highly expressed in the embryonic than the postnatal stages, acts as a paracellular channel for small cations, such as Na+, similar to the typical channel-type claudins claudin-2 and -15. Claudin-21 also allows the paracellular passage of larger solutes. Our findings suggest that claudin-21-based TJs allow the passage of small and larger solutes by both paracellular channel-based and some additional mechanisms. äClaudin-21 Has a Paracellular Channel Role at Tight Junctions (epmc).pdf DeepDyve Pubget Overpricing