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Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Database+(Oxford) 2016 ; 2016 (ä): ä Nephropedia Template TP
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CoDNaS 2 0: a comprehensive database of protein conformational diversity in the native state #MMPMID27022160
Monzon AM; Rohr CO; Fornasari MS; Parisi G
Database (Oxford) 2016[]; 2016 (ä): ä PMID27022160show ga
CoDNaS (conformational diversity of the native state) is a protein conformational diversity database. Conformational diversity describes structural differences between conformers that define the native state of proteins. It is a key concept to understand protein function and biological processes related to protein functions. CoDNaS offers a well curated database that is experimentally driven, thoroughly linked, and annotated. CoDNaS facilitates the extraction of key information on small structural differences based on protein movements. CoDNaS enables users to easily relate the degree of conformational diversity with physical, chemical and biological properties derived from experiments on protein structure and biological characteristics. The new version of CoDNaS includes ?70% of all available protein structures, and new tools have been added that run sequence searches, display structural flexibility profiles and allow users to browse the database for different structural classes. These tools facilitate the exploration of protein conformational diversity and its role in protein function.Database URL:http://ufq.unq.edu.ar/codnas