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A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1136/bmjopen-2015-010869 http://scihub22266oqcxt.onion/10.1136/bmjopen-2015-010869 C4809071!4809071 !27006347     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=27006347 &cmd=llinks): Failed to open stream: HTTP request failed! 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Investigating kidney donation as a risk factor for hypertension and microalbuminuria: findings from the Swiss prospective follow-up of living kidney donors |pdf=|usr=}}{{27006347 }} gab.com Text Investigating kidney donation as a risk factor for hypertension and microalbuminuria: findings from the Swiss prospective follow-up of living kidney donors JO: BMJ Open http://www.kidney.de/pget.php?&tw=1&pmid=27006347 #FOAvip OBJECTIVES: To assess the role of nephrectomy as a risk factor for the development of hypertension and microalbuminuria. DESIGN: Prospective, long-term follow-up study. SETTING: Swiss Organ Living-Donor Health Registry. PARTICIPANTS: All living kidney donors in Switzerland between 1993 and 2009. INTERVENTIONS: Data on health status and renal function before 1 year and biennially after donation were collected. PRIMARY AND SECONDARY OUTCOME MEASURES: Comparison of 1-year and 5-year occurrences of hypertension among normotensive donors with 1-year and 5-year estimates from the Framingham hypertension risk score. Multivariate random intercept models were used to investigate changes of albumin excretion after donation, correcting for repeated measurements and cofactors such as age, male gender and body mass index. RESULTS: A total of 1214 donors contributed 3918 data entries with a completed biennial follow-up rate of 74% during a 10-year period. Mean (SD) follow-up of donors was 31.6 months (34.4). Median age at donation was 50.5 years (IQR 42.2-58.8); 806 donors (66.4%) were women. Donation increased the risk of hypertension after 1 year by 3.64 (95% CI 3.52 to 3.76; p<0.001). Those participants remaining normotensive 1 year after donation return to a risk similar to that of the healthy Framingham population. Microalbuminuria before donation was dependent on donor age but not on the presence of hypertension. After nephrectomy, hypertension became the main driver for changes in albumin excretion (OR 1.19; 95% CI 0.13 to 2.25; p=0.03) and donor age had no effect. CONCLUSIONS: Nephrectomy propagates hypertension and increases susceptibility for the development of hypertension-induced microalbuminuria. Twit Text FOAVip Investigating kidney donation as a risk factor for hypertension and microalbuminuria: findings from the Swiss prospective follow-up of living kidney donors ????BMJ Open http://www.kidney.de/pget.php?&tw=1&pmid=27006347 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27006347 #FOAvip English Wikipedia <ref>{{Cite pmid|27006347 }}</ref> Investigating kidney donation as a risk factor for hypertension and microalbuminuria: findings from the Swiss prospective follow-up of living kidney donors #MMPMID27006347 Thiel GT ; Nolte C ; Tsinalis D ; Steiger J ; Bachmann LM BMJ Open 2016[Mar]; 6 (3 ): e010869 PMID27006347 show ga OBJECTIVES: To assess the role of nephrectomy as a risk factor for the development of hypertension and microalbuminuria. DESIGN: Prospective, long-term follow-up study. SETTING: Swiss Organ Living-Donor Health Registry. PARTICIPANTS: All living kidney donors in Switzerland between 1993 and 2009. INTERVENTIONS: Data on health status and renal function before 1 year and biennially after donation were collected. PRIMARY AND SECONDARY OUTCOME MEASURES: Comparison of 1-year and 5-year occurrences of hypertension among normotensive donors with 1-year and 5-year estimates from the Framingham hypertension risk score. Multivariate random intercept models were used to investigate changes of albumin excretion after donation, correcting for repeated measurements and cofactors such as age, male gender and body mass index. RESULTS: A total of 1214 donors contributed 3918 data entries with a completed biennial follow-up rate of 74% during a 10-year period. Mean (SD) follow-up of donors was 31.6 months (34.4). Median age at donation was 50.5 years (IQR 42.2-58.8); 806 donors (66.4%) were women. Donation increased the risk of hypertension after 1 year by 3.64 (95% CI 3.52 to 3.76; p<0.001). Those participants remaining normotensive 1 year after donation return to a risk similar to that of the healthy Framingham population. Microalbuminuria before donation was dependent on donor age but not on the presence of hypertension. After nephrectomy, hypertension became the main driver for changes in albumin excretion (OR 1.19; 95% CI 0.13 to 2.25; p=0.03) and donor age had no effect. CONCLUSIONS: Nephrectomy propagates hypertension and increases susceptibility for the development of hypertension-induced microalbuminuria. |Adult [MESH] |Aged [MESH] |Albuminuria/*epidemiology/etiology [MESH] |Blood Pressure [MESH] |Creatinine/analysis [MESH] |Female [MESH] |Follow-Up Studies [MESH] |Glomerular Filtration Rate [MESH] |Humans [MESH] |Hypertension/*epidemiology/etiology [MESH] |Kidney Transplantation/*methods [MESH] |Living Donors/*statistics & numerical data [MESH] |Logistic Models [MESH] |Male [MESH] |Middle Aged [MESH] |Multivariate Analysis [MESH] |Nephrectomy/*adverse effects [MESH] |Prospective Studies [MESH] |Risk Factors [MESH]Investigating kidney donation as a risk factor for hypertension and (epmc).pdf DeepDyve Pubget Overpricing