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10.1016/j.ymeth.2015.11.026 http://scihub22266oqcxt.onion/10.1016/j.ymeth.2015.11.026 C4808352!4808352!26655524     free     free     free       Methods 2016 ; 98 (ä): 4-9 Nephropedia Template TP {{tp|p=26655524|t=2016. The Origin of In Situ Hybridization - a Personal History |pdf=|usr=}}{{26655524}} gab.com Text The Origin of In Situ Hybridization - a Personal History JO: Methods http://www.kidney.de/pget.php?&tw=1&pmid=26655524 #FOAvip In situ hybridization is the technique by which specific RNA or DNA molecules are detected in cytological preparations. Basically it involves formation of a hybrid molecule between an endogenous single-stranded RNA or DNA in the cell and a complementary single-stranded RNA or DNA probe. In its original form the probe was labeled with 3H and the hybrid was detected by autoradiography. The first successful experiments in 1968 involved detection of the highly amplified ribosomal DNA in oocytes of the frog Xenopus, followed soon after by the reiterated ?satellite DNA? in mouse and Drosophila chromosomes. Fluorescent probes were developed about ten years later. Twit Text FOAVip The Origin of In Situ Hybridization - a Personal History ????Methods http://www.kidney.de/pget.php?&tw=1&pmid=26655524 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26655524 #FOAvip English Wikipedia <ref>{{Cite pmid|26655524}}</ref> The Origin of In Situ Hybridization - a Personal History #MMPMID26655524 Gall JG Methods 2016[Apr]; 98 (ä): 4-9 PMID26655524show ga In situ hybridization is the technique by which specific RNA or DNA molecules are detected in cytological preparations. Basically it involves formation of a hybrid molecule between an endogenous single-stranded RNA or DNA in the cell and a complementary single-stranded RNA or DNA probe. In its original form the probe was labeled with 3H and the hybrid was detected by autoradiography. The first successful experiments in 1968 involved detection of the highly amplified ribosomal DNA in oocytes of the frog Xenopus, followed soon after by the reiterated ?satellite DNA? in mouse and Drosophila chromosomes. Fluorescent probes were developed about ten years later. äThe Origin of In Situ Hybridization - a Personal History (epmc).pdf DeepDyve Pubget Overpricing