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2016 ; 26
(ä): 53-61
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Frailty assessment instruments: Systematic characterization of the uses and
contexts of highly-cited instruments
#MMPMID26674984
Buta BJ
; Walston JD
; Godino JG
; Park M
; Kalyani RR
; Xue QL
; Bandeen-Roche K
; Varadhan R
Ageing Res Rev
2016[Mar]; 26
(ä): 53-61
PMID26674984
show ga
The medical syndrome of frailty is widely recognized, yet debate remains over how
best to measure it in clinical and research settings. This study reviewed the
frailty-related research literature by (a) comprehensively cataloging the wide
array of instruments that have been utilized to measure frailty, and (b)
systematically categorizing the different purposes and contexts of use for
frailty instruments frequently cited in the research literature. We identified 67
frailty instruments total; of these, nine were highly-cited (? 200 citations). We
randomly sampled and reviewed 545 English-language articles citing at least one
highly-cited instrument. We estimated the total number of uses, and classified
use into eight categories: risk assessment for adverse health outcomes (31% of
all uses); etiological studies of frailty (22%); methodology studies (14%);
biomarker studies (12%); inclusion/exclusion criteria (10%); estimating
prevalence as primary goal (5%); clinical decision-making (2%); and
interventional targeting (2%). The most common assessment context was
observational studies of older community-dwelling adults. Physical Frailty
Phenotype was the most used frailty instrument in the research literature,
followed by the Deficit Accumulation Index and the Vulnerable Elders Survey. This
study provides an empirical evaluation of the current uses of frailty
instruments, which may be important to consider when selecting instruments for
clinical or research purposes. We recommend careful consideration in the
selection of a frailty instrument based on the intended purpose, domains
captured, and how the instrument has been used in the past. Continued efforts are
needed to study the validity and feasibility of these instruments.
|Aged, 80 and over
[MESH]
|Frail Elderly/*statistics & numerical data
[MESH]