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10.3748/wjg.v22.i12.3305 http://scihub22266oqcxt.onion/10.3748/wjg.v22.i12.3305 C4806188!4806188!27022212     free     free     free Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       World+J+Gastroenterol 2016 ; 22 (12): 3305-14 Nephropedia Template TP {{tp|p=27022212|t=2016. Latest developments in precancerous lesions of hepatocellular carcinoma |pdf=|usr=}}{{27022212}} gab.com Text Latest developments in precancerous lesions of hepatocellular carcinoma JO: World J Gastroenterol http://www.kidney.de/pget.php?&tw=1&pmid=27022212 #FOAvip Hepatocarcinogenesis in human chronic liver diseases is a multi-step process in which hepatic precancerous lesions progress into early hepatocellular carcinoma (HCC) and progressed HCC, and the close surveillance and treatment of these lesions will help improve the survival rates of patients with HCC. The rapid development and extensive application of imaging technology have facilitated the discovery of nodular lesions of ambiguous significance, such as dysplastic nodules. Further investigations showed that these nodules may be hepatic precancerous lesions, and they often appear in patients with liver cirrhosis. Although the morphology of these nodules is not sufficient to support a diagnosis of malignant tumor, these nodules are closely correlated with the occurrence of HCC, as indicated by long-term follow-up studies. In recent years, the rapid development and wide application of pathology, molecular genetics and imaging technology have elucidated the characteristics of precancerous lesions. Based on our extensive review of the relevant literature, this article focuses on evidence indicating that high-grade dysplastic nodules are more likely to transform into HCC than low-grade dysplastic nodules based on clinical, pathological, molecular genetic and radiological assessments. In addition, evidence supporting the precancerous nature of large cell change in hepatitis B virus-related HCC is discussed. Twit Text FOAVip Latest developments in precancerous lesions of hepatocellular carcinoma ????World J Gastroenterol http://www.kidney.de/pget.php?&tw=1&pmid=27022212 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27022212 #FOAvip English Wikipedia <ref>{{Cite pmid|27022212}}</ref> Latest developments in precancerous lesions of hepatocellular carcinoma #MMPMID27022212 Niu ZS; Niu XJ; Wang WH; Zhao J World J Gastroenterol 2016[Mar]; 22 (12): 3305-14 PMID27022212show ga Hepatocarcinogenesis in human chronic liver diseases is a multi-step process in which hepatic precancerous lesions progress into early hepatocellular carcinoma (HCC) and progressed HCC, and the close surveillance and treatment of these lesions will help improve the survival rates of patients with HCC. The rapid development and extensive application of imaging technology have facilitated the discovery of nodular lesions of ambiguous significance, such as dysplastic nodules. Further investigations showed that these nodules may be hepatic precancerous lesions, and they often appear in patients with liver cirrhosis. Although the morphology of these nodules is not sufficient to support a diagnosis of malignant tumor, these nodules are closely correlated with the occurrence of HCC, as indicated by long-term follow-up studies. In recent years, the rapid development and wide application of pathology, molecular genetics and imaging technology have elucidated the characteristics of precancerous lesions. Based on our extensive review of the relevant literature, this article focuses on evidence indicating that high-grade dysplastic nodules are more likely to transform into HCC than low-grade dysplastic nodules based on clinical, pathological, molecular genetic and radiological assessments. In addition, evidence supporting the precancerous nature of large cell change in hepatitis B virus-related HCC is discussed. äLatest developments in precancerous lesions of hepatocellular carcinom(epmc).pdf DeepDyve Pubget Overpricing