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10.1186/s13000-016-0481-7 http://scihub22266oqcxt.onion/10.1186/s13000-016-0481-7 C4802878!4802878!27004798     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Diagn+Pathol 2016 ; 11 (ä): ä Nephropedia Template TP {{tp|p=27004798|t=2016. Poorly differentiated clusters (PDC) in colorectal cancer: what is and ought to be known |pdf=|usr=}}{{27004798}} gab.com Text Poorly differentiated clusters (PDC) in colorectal cancer: what is and ought to be known JO: Diagn Pathol http://www.kidney.de/pget.php?&tw=1&pmid=27004798 #FOAvip Background: The counting of poorly differentiated clusters of 5 or more cancer cells lacking a gland-like structure in a tumor mass has recently been identified among the histological features predictive of poor prognosis in colorectal cancer. Main body: Poorly differentiated clusters can easily be recognized in the histological sections of colorectal cancer routinely stained with haematoxylin and eosin. Despite some limitations related to specimen fragmentation, counting can also be assessed in endoscopic biopsies. Based on the number of poorly differentiated clusters that appear under a microscopic field of a ×20 objective lens (i.e., a microscopic field with a major axis of 1 mm), colorectal cancer can be graded into malignancies as follows: tumors with <5 clusters as grade 1, tumors with 5 to 9 clusters as grade 2, and tumors with ?10 clusters as grade 3. High poorly differentiated cluster counts are significantly associated with peri-neural and lympho-vascular invasion, the presence of nodal metastases or micrometastases, as well as shorter overall and progression free survival to colorectal cancer. Conclusion: The morphological aspects and clinical relevance of poorly differentiated clusters counting in colorectal cancer are discussed in this review. Twit Text FOAVip Poorly differentiated clusters (PDC) in colorectal cancer: what is and ought to be known ????Diagn Pathol http://www.kidney.de/pget.php?&tw=1&pmid=27004798 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27004798 #FOAvip English Wikipedia <ref>{{Cite pmid|27004798}}</ref> Poorly differentiated clusters (PDC) in colorectal cancer: what is and ought to be known #MMPMID27004798 Reggiani Bonetti L; Barresi V; Bettelli S; Domati F; Palmiere C Diagn Pathol 2016[]; 11 (ä): ä PMID27004798show ga Background: The counting of poorly differentiated clusters of 5 or more cancer cells lacking a gland-like structure in a tumor mass has recently been identified among the histological features predictive of poor prognosis in colorectal cancer. Main body: Poorly differentiated clusters can easily be recognized in the histological sections of colorectal cancer routinely stained with haematoxylin and eosin. Despite some limitations related to specimen fragmentation, counting can also be assessed in endoscopic biopsies. Based on the number of poorly differentiated clusters that appear under a microscopic field of a ×20 objective lens (i.e., a microscopic field with a major axis of 1 mm), colorectal cancer can be graded into malignancies as follows: tumors with <5 clusters as grade 1, tumors with 5 to 9 clusters as grade 2, and tumors with ?10 clusters as grade 3. High poorly differentiated cluster counts are significantly associated with peri-neural and lympho-vascular invasion, the presence of nodal metastases or micrometastases, as well as shorter overall and progression free survival to colorectal cancer. Conclusion: The morphological aspects and clinical relevance of poorly differentiated clusters counting in colorectal cancer are discussed in this review. äPoorly differentiated clusters (PDC) in colorectal cancer: what is and(epmc).pdf DeepDyve Pubget Overpricing