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10.1016/j.ijcard.2016.01.009

http://scihub22266oqcxt.onion/10.1016/j.ijcard.2016.01.009
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suck abstract from ncbi


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pmid26788685      Int+J+Cardiol 2016 ; 206 (ä): 116-21
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  • Blood pressure and all-cause mortality among patients with type 2 diabetes: Blood pressure and death risk in diabetic patients #MMPMID26788685
  • Li W; Katzmarzyk PT; Horswell R; Wang Y; Johnson J; Hu G
  • Int J Cardiol 2016[Mar]; 206 (ä): 116-21 PMID26788685show ga
  • Background: The recommended goal for blood pressure (BP) control has recently been adjusted for people with diabetes, but the optimal BP control range for the diabetic population is still uncertain. Methods: We performed a prospective cohort study of 35,261 patients with type 2 diabetes. Cox proportional hazards regression models were used to estimate the association of BP with all-cause mortality. Results: During a mean follow-up period of 8.7 years, 4,199 deaths were identified. The multivariable-adjusted hazard ratios of all-cause mortality associated with different levels of systolic/diastolic BP (<110/65, 110?119/65?69, 120?129/70?80, 130?139/80?90 [reference group], 140?159/90?100, and ?160/100 mmHg) were 1.70 (95% confidence interval [CI] 1.42?2.04), 1.26 (95% CI 1.07?1.50), 0.99 (95% CI 0.86?1.12), 1.00, 0.92 (95% CI 0.82?1.03), and 1.10 (95% CI 0.98?1.23) using baseline BP measurements, and 2.62 (95% CI 2.00?3.44), 1.77 (95% CI 1.51?2.09), 1.22 (95% CI 1.09?1.36), 1.00, 0.90 (95% CI 0.82?1.00), and 0.98 (95% CI 0.86?1.12) using an updated mean value of BP during follow-up, respectively. The U-shaped associations were confirmed in both African American and white patients, in both men and women, in those who were or were not taking antihypertensive drugs; and in patients aged 30?49 years and 50?59 years. Conclusions: The current study found a U-shaped association between BP at baseline and during follow-up and the risk of all-cause mortality among patients with type 2 diabetes.
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