Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1186/s12859-016-0982-0 http://scihub22266oqcxt.onion/10.1186/s12859-016-0982-0 C4802584!4802584!27001685     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       BMC+Bioinformatics 2016 ; 17 (ä): ä Nephropedia Template TP {{tp|p=27001685|t=2016. Modeling the integration of bacterial rRNA fragments into the human cancer genome |pdf=|usr=}}{{27001685}} gab.com Text Modeling the integration of bacterial rRNA fragments into the human cancer genome JO: BMC Bioinformatics http://www.kidney.de/pget.php?&tw=1&pmid=27001685 #FOAvip Background: Cancer is a disease driven by the accumulation of genomic alterations, including the integration of exogenous DNA into the human somatic genome. We previously identified in silico evidence of DNA fragments from a Pseudomonas-like bacteria integrating into the 5?-UTR of four proto-oncogenes in stomach cancer sequencing data. The functional and biological consequences of these bacterial DNA integrations remain unknown. Results: Modeling of these integrations suggests that the previously identified sequences cover most of the sequence flanking the junction between the bacterial and human DNA. Further examination of these reads reveals that these integrations are rich in guanine nucleotides and the integrated bacterial DNA may have complex transcript secondary structures. Conclusions: The models presented here lay the foundation for future experiments to test if bacterial DNA integrations alter the transcription of the human genes. Electronic supplementary material: The online version of this article (doi:10.1186/s12859-016-0982-0) contains supplementary material, which is available to authorized users. Twit Text FOAVip Modeling the integration of bacterial rRNA fragments into the human cancer genome ????BMC Bioinformatics http://www.kidney.de/pget.php?&tw=1&pmid=27001685 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27001685 #FOAvip English Wikipedia <ref>{{Cite pmid|27001685}}</ref> Modeling the integration of bacterial rRNA fragments into the human cancer genome #MMPMID27001685 Sieber KB; Gajer P; Dunning Hotopp JC BMC Bioinformatics 2016[]; 17 (ä): ä PMID27001685show ga Background: Cancer is a disease driven by the accumulation of genomic alterations, including the integration of exogenous DNA into the human somatic genome. We previously identified in silico evidence of DNA fragments from a Pseudomonas-like bacteria integrating into the 5?-UTR of four proto-oncogenes in stomach cancer sequencing data. The functional and biological consequences of these bacterial DNA integrations remain unknown. Results: Modeling of these integrations suggests that the previously identified sequences cover most of the sequence flanking the junction between the bacterial and human DNA. Further examination of these reads reveals that these integrations are rich in guanine nucleotides and the integrated bacterial DNA may have complex transcript secondary structures. Conclusions: The models presented here lay the foundation for future experiments to test if bacterial DNA integrations alter the transcription of the human genes. Electronic supplementary material: The online version of this article (doi:10.1186/s12859-016-0982-0) contains supplementary material, which is available to authorized users. äModeling the integration of bacterial rRNA fragments into the human ca(epmc).pdf DeepDyve Pubget Overpricing