Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1016/j.coi.2015.12.009 http://scihub22266oqcxt.onion/10.1016/j.coi.2015.12.009 C4801724!4801724!26774863     free     free     free       Curr+Opin+Immunol 2016 ; 39 (ä): 39-43 Nephropedia Template TP {{tp|p=26774863|t=2016. TREG STABILITY: TO BE OR NOT TO BE |pdf=|usr=}}{{26774863}} gab.com Text TREG STABILITY: TO BE OR NOT TO BE JO: Curr Opin Immunol http://www.kidney.de/pget.php?&tw=1&pmid=26774863 #FOAvip Regulatory T cell (Treg) stability has been primarily determined by the maintained expression of the transcription factor Forkhead box P3 (Foxp3). However, Tregs can exhibit instability while maintaining Foxp3 expression, requiring a re-examination of what defines Treg stability. Recent work suggests that the establishment and stability of Tregs is mediated by a number of mechanisms besides Foxp3 expression, such as epigenetic modifications, Foxo1/3a localization, expression of Eos and signaling via Neuropilin-1. Additional studies may help to define approaches that can undermine Treg stability in cancer or enhance Treg stability in transplantation, autoimmune or inflammatory diseases and therefore have substantial therapeutic utility. In this review, we will discuss how Treg stability is defined and the mechanisms utilized to maintain stability. Twit Text FOAVip TREG STABILITY: TO BE OR NOT TO BE ????Curr Opin Immunol http://www.kidney.de/pget.php?&tw=1&pmid=26774863 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26774863 #FOAvip English Wikipedia <ref>{{Cite pmid|26774863}}</ref> TREG STABILITY: TO BE OR NOT TO BE #MMPMID26774863 Overacre AE; Vignali DA Curr Opin Immunol 2016[Apr]; 39 (ä): 39-43 PMID26774863show ga Regulatory T cell (Treg) stability has been primarily determined by the maintained expression of the transcription factor Forkhead box P3 (Foxp3). However, Tregs can exhibit instability while maintaining Foxp3 expression, requiring a re-examination of what defines Treg stability. Recent work suggests that the establishment and stability of Tregs is mediated by a number of mechanisms besides Foxp3 expression, such as epigenetic modifications, Foxo1/3a localization, expression of Eos and signaling via Neuropilin-1. Additional studies may help to define approaches that can undermine Treg stability in cancer or enhance Treg stability in transplantation, autoimmune or inflammatory diseases and therefore have substantial therapeutic utility. In this review, we will discuss how Treg stability is defined and the mechanisms utilized to maintain stability. äTREG STABILITY: TO BE OR NOT TO BE (epmc).pdf DeepDyve Pubget Overpricing