Signaling in host-associated microbial communities #MMPMID26967294
Fischbach MA; Segre JA
Cell 2016[Mar]; 164 (6): 1288-300 PMID26967294show ga
Human-associated microbiota form and stabilize communities based on interspecies interactions. We review how these microbe-microbe and microbe-host interactions are communicated to shape communities over a human?s lifespan, including periods of health and disease. Modeling and dissecting signaling in host-associated communities is crucial to understand their function, and will open the door to therapies that prevent or correct microbial community dysfunction to promote health and treat disease.