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10.1073/pnas.1524290113 http://scihub22266oqcxt.onion/10.1073/pnas.1524290113 C4801311!4801311!26929342     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Proc+Natl+Acad+Sci+U+S+A 2016 ; 113 (11): 3042-7 Nephropedia Template TP {{tp|p=26929342|t=2016. Type VI secretion system sheaths as nanoparticles for antigen display |pdf=|usr=}}{{26929342}} gab.com Text Type VI secretion system sheaths as nanoparticles for antigen display JO: Proc Natl Acad Sci U S A http://www.kidney.de/pget.php?&tw=1&pmid=26929342 #FOAvip Critical aspects that limit use of nanoparticles as vaccine delivery systems include the technical difficulty of preparing particles under conditions that allow controlled protein loading and folding. Biologic nanoparticles offer advantages over chemically derived particles that require harsh organic solvents for preparation. Here, we demonstrate that the multimeric sheath structure of the bacterial type 6 secretion system (T6SS) can be exploited to generate particles that display on their surface many copies of specific proteins of interest. T6SS sheaths represent a functional vaccine delivery system with remarkable flexibility due to the ability to biochemically modify these structures to expand or enhance potential immunogenicity. Twit Text FOAVip Type VI secretion system sheaths as nanoparticles for antigen display ????Proc Natl Acad Sci U S A http://www.kidney.de/pget.php?&tw=1&pmid=26929342 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26929342 #FOAvip English Wikipedia <ref>{{Cite pmid|26929342}}</ref> Type VI secretion system sheaths as nanoparticles for antigen display #MMPMID26929342 Del Tordello E; Danilchanka O; McCluskey AJ; Mekalanos JJ Proc Natl Acad Sci U S A 2016[Mar]; 113 (11): 3042-7 PMID26929342show ga Critical aspects that limit use of nanoparticles as vaccine delivery systems include the technical difficulty of preparing particles under conditions that allow controlled protein loading and folding. Biologic nanoparticles offer advantages over chemically derived particles that require harsh organic solvents for preparation. Here, we demonstrate that the multimeric sheath structure of the bacterial type 6 secretion system (T6SS) can be exploited to generate particles that display on their surface many copies of specific proteins of interest. T6SS sheaths represent a functional vaccine delivery system with remarkable flexibility due to the ability to biochemically modify these structures to expand or enhance potential immunogenicity. äType VI secretion system sheaths as nanoparticles for antigen display (epmc).pdf DeepDyve Pubget Overpricing