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10.1038/nri3863 http://scihub22266oqcxt.onion/10.1038/nri3863 C4801113!4801113!26160612     free     free     free       Nat+Rev+Immunol 2015 ; 15 (8): 500-10 Nephropedia Template TP {{tp|p=26160612|t=2015. Iron homeostasis in host defence and inflammation |pdf=|usr=}}{{26160612}} gab.com Text Iron homeostasis in host defence and inflammation JO: Nat Rev Immunol http://www.kidney.de/pget.php?&tw=1&pmid=26160612 #FOAvip Iron is an essential trace element for multicellular organisms and nearly all microorganisms. Although iron is abundant in the environment, common forms of iron are minimally soluble and therefore poorly accessible to biological organisms. Microorganisms entering a mammalian host face multiple mechanisms that further restrict their ability to obtain iron and thereby limit their pathogenicity. Iron levels also modulate host defence, as iron content in macrophages regulates their cytokine production. Here, we review recent advances that highlight the role of systemic and cellular iron-regulating mechanisms in protecting hosts from infection, emphasizing aspects that are applicable to human health and disease. Twit Text FOAVip Iron homeostasis in host defence and inflammation ????Nat Rev Immunol http://www.kidney.de/pget.php?&tw=1&pmid=26160612 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26160612 #FOAvip English Wikipedia <ref>{{Cite pmid|26160612}}</ref> Iron homeostasis in host defence and inflammation #MMPMID26160612 Ganz T; Nemeth E Nat Rev Immunol 2015[Aug]; 15 (8): 500-10 PMID26160612show ga Iron is an essential trace element for multicellular organisms and nearly all microorganisms. Although iron is abundant in the environment, common forms of iron are minimally soluble and therefore poorly accessible to biological organisms. Microorganisms entering a mammalian host face multiple mechanisms that further restrict their ability to obtain iron and thereby limit their pathogenicity. Iron levels also modulate host defence, as iron content in macrophages regulates their cytokine production. Here, we review recent advances that highlight the role of systemic and cellular iron-regulating mechanisms in protecting hosts from infection, emphasizing aspects that are applicable to human health and disease. äIron homeostasis in host defence and inflammation (epmc).pdf DeepDyve Pubget Overpricing