Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=26983021
&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215
Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26983021
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 OMICS
2016 ; 20
(3
): 139-51
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
GeneAnalytics: An Integrative Gene Set Analysis Tool for Next Generation
Sequencing, RNAseq and Microarray Data
#MMPMID26983021
Ben-Ari Fuchs S
; Lieder I
; Stelzer G
; Mazor Y
; Buzhor E
; Kaplan S
; Bogoch Y
; Plaschkes I
; Shitrit A
; Rappaport N
; Kohn A
; Edgar R
; Shenhav L
; Safran M
; Lancet D
; Guan-Golan Y
; Warshawsky D
; Shtrichman R
OMICS
2016[Mar]; 20
(3
): 139-51
PMID26983021
show ga
Postgenomics data are produced in large volumes by life sciences and clinical
applications of novel omics diagnostics and therapeutics for precision medicine.
To move from "data-to-knowledge-to-innovation," a crucial missing step in the
current era is, however, our limited understanding of biological and clinical
contexts associated with data. Prominent among the emerging remedies to this
challenge are the gene set enrichment tools. This study reports on GeneAnalytics?
( geneanalytics.genecards.org ), a comprehensive and easy-to-apply gene set
analysis tool for rapid contextualization of expression patterns and functional
signatures embedded in the postgenomics Big Data domains, such as Next Generation
Sequencing (NGS), RNAseq, and microarray experiments. GeneAnalytics'
differentiating features include in-depth evidence-based scoring algorithms, an
intuitive user interface and proprietary unified data. GeneAnalytics employs the
LifeMap Science's GeneCards suite, including the GeneCards®--the human gene
database; the MalaCards-the human diseases database; and the PathCards--the
biological pathways database. Expression-based analysis in GeneAnalytics relies
on the LifeMap Discovery®--the embryonic development and stem cells database,
which includes manually curated expression data for normal and diseased tissues,
enabling advanced matching algorithm for gene-tissue association. This assists in
evaluating differentiation protocols and discovering biomarkers for tissues and
cells. Results are directly linked to gene, disease, or cell "cards" in the
GeneCards suite. Future developments aim to enhance the GeneAnalytics algorithm
as well as visualizations, employing varied graphical display items. Such
attributes make GeneAnalytics a broadly applicable postgenomics data analyses and
interpretation tool for translation of data to knowledge-based innovation in
various Big Data fields such as precision medicine, ecogenomics, nutrigenomics,
pharmacogenomics, vaccinomics, and others yet to emerge on the postgenomics
horizon.
|*Gene Regulatory Networks
[MESH]
|*Genome, Human
[MESH]
|*Software
[MESH]
|Algorithms
[MESH]
|Computational Biology/*methods
[MESH]
|Data Mining
[MESH]
|Databases, Factual
[MESH]
|Databases, Genetic
[MESH]
|High-Throughput Nucleotide Sequencing/*statistics & numerical data
[MESH]