Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1097/CCM.0000000000000224 http://scihub22266oqcxt.onion/10.1097/CCM.0000000000000224 C4799649!4799649!24557420     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 298.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 298.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 298.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 298.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Crit+Care+Med 2014 ; 42 (6): 1442-54 Nephropedia Template TP {{tp|p=24557420|t=2014. Randomized ICU Trials Do Not Demonstrate an Association Between Interventions That Reduce Delirium Duration and Short-Term Mortality: A Systematic Review and Meta-Analysis |pdf=|usr=}}{{24557420}} gab.com Text Randomized ICU Trials Do Not Demonstrate an Association Between Interventions That Reduce Delirium Duration and Short-Term Mortality: A Systematic Review and Meta-Analysis JO: Crit Care Med http://www.kidney.de/pget.php?&tw=1&pmid=24557420 #FOAvip Background: Interventions that reduce delirium duration may also lower short-term mortality. We reviewed randomized trials of adult ICU patients of interventions hypothesized to reduce delirium burden to determine whether interventions that are more effective at reducing delirium duration are associated with a reduction in short-term mortality. Search Methods: We searched CINHAHL, EMBASE, MEDLINE and the Cochrane databases from 2001 through 2012. Citations were screened for randomized trials that enrolled critically ill adults, evaluated delirium at least daily, compared a drug or non-drug intervention hypothesized to reduce delirium burden with standard care (or control), and reported delirium duration and/or short-term mortality (?45 days). In duplicate, we abstracted trial characteristics and results and evaluated quality using the Cochrane risk of bias tool. We performed random effects model meta-analyses and meta-regressions. Results: We included 17 trials enrolling 2,849 patients which evaluated a pharmacologic intervention (n=13) [dexmedetomidine (n=6); an antipsychotic (n=4); rivastigmine (n=2); and clonidine (n=1)], a multimodal intervention (n=2) [spontaneous-awakening (n=2)]; or a non-pharmacologic intervention (n=2) [early mobilization (n=1); increased perfusion (n=1)]. Overall, average delirium duration was lower in the intervention groups [difference = ?0.64 days; 95% CI, ?1.15 to ?0.13; P = 0.01) being reduced by ?3 days in 3 studies, 0.1 to < 3 days in 6 studies, 0 days in 7 studies and < 0 days in 1. Across interventions, for 13 studies where short-term mortality was reported, short-term mortality was not reduced (risk ratio = 0.90; 95% CI, 0.76 to 1.06; P = 0.19). Across 13 studies that reported mortality, meta-regression revealed that delirium duration was not associated with reduced short-term mortality (P = 0.11). Conclusions: A review of current evidence fails to support that ICU interventions that reduce delirium duration reduce short-term mortality. Larger controlled studies are needed to establish this relationship. Twit Text FOAVip Randomized ICU Trials Do Not Demonstrate an Association Between Interventions That Reduce Delirium Duration and Short-Term Mortality: A Systematic Review and Meta-Analysis ????Crit Care Med http://www.kidney.de/pget.php?&tw=1&pmid=24557420 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24557420 #FOAvip English Wikipedia <ref>{{Cite pmid|24557420}}</ref> Randomized ICU Trials Do Not Demonstrate an Association Between Interventions That Reduce Delirium Duration and Short-Term Mortality: A Systematic Review and Meta-Analysis #MMPMID24557420 Al-Qadheeb NS; Balk EM; Fraser GL; Skrobik Y; Riker RR; Kress JP; Whitehead S; Devlin JW Crit Care Med 2014[Jun]; 42 (6): 1442-54 PMID24557420show ga Background: Interventions that reduce delirium duration may also lower short-term mortality. We reviewed randomized trials of adult ICU patients of interventions hypothesized to reduce delirium burden to determine whether interventions that are more effective at reducing delirium duration are associated with a reduction in short-term mortality. Search Methods: We searched CINHAHL, EMBASE, MEDLINE and the Cochrane databases from 2001 through 2012. Citations were screened for randomized trials that enrolled critically ill adults, evaluated delirium at least daily, compared a drug or non-drug intervention hypothesized to reduce delirium burden with standard care (or control), and reported delirium duration and/or short-term mortality (?45 days). In duplicate, we abstracted trial characteristics and results and evaluated quality using the Cochrane risk of bias tool. We performed random effects model meta-analyses and meta-regressions. Results: We included 17 trials enrolling 2,849 patients which evaluated a pharmacologic intervention (n=13) [dexmedetomidine (n=6); an antipsychotic (n=4); rivastigmine (n=2); and clonidine (n=1)], a multimodal intervention (n=2) [spontaneous-awakening (n=2)]; or a non-pharmacologic intervention (n=2) [early mobilization (n=1); increased perfusion (n=1)]. Overall, average delirium duration was lower in the intervention groups [difference = ?0.64 days; 95% CI, ?1.15 to ?0.13; P = 0.01) being reduced by ?3 days in 3 studies, 0.1 to < 3 days in 6 studies, 0 days in 7 studies and < 0 days in 1. Across interventions, for 13 studies where short-term mortality was reported, short-term mortality was not reduced (risk ratio = 0.90; 95% CI, 0.76 to 1.06; P = 0.19). Across 13 studies that reported mortality, meta-regression revealed that delirium duration was not associated with reduced short-term mortality (P = 0.11). Conclusions: A review of current evidence fails to support that ICU interventions that reduce delirium duration reduce short-term mortality. Larger controlled studies are needed to establish this relationship. äRandomized ICU Trials Do Not Demonstrate an Association Between Interv(epmc).pdf DeepDyve Pubget Overpricing