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10.1097/PPO.0000000000000003 http://scihub22266oqcxt.onion/10.1097/PPO.0000000000000003 C4797645!4797645!24270349     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Cancer+J 2013 ; 19 (6): 502-10 Nephropedia Template TP {{tp|p=24270349|t=2013. Inflammatory mediator prostaglandin E2 in colorectal cancer |pdf=|usr=}}{{24270349}} gab.com Text Inflammatory mediator prostaglandin E2 in colorectal cancer JO: Cancer J http://www.kidney.de/pget.php?&tw=1&pmid=24270349 #FOAvip It is widely accepted that dietary fats and chronic inflammation are risk factors for developing colorectal cancer. Arachidonic acid is a major component of animal fats and the bioactive lipids produced from this substrate play critical roles in a variety of biologic processes, including cancer. Cyclooxygenase-derived prostaglandin E2 (PGE2) is a known pro-inflammatory lipid mediator and promotes tumor progression. Metabolism of arachidonic acid by the cyclooxygenase pathway provides one mechanism for the contribution of dietary fats and chronic inflammation to carcinogenesis. In this review, we highlight recent advances in our understanding of how pro-inflammatory mediator PGE2 promotes colorectal cancer immune evasion. These findings may provide a rationale for the development of new therapeutic approaches to subvert tumor-induced immunosuppression. Twit Text FOAVip Inflammatory mediator prostaglandin E2 in colorectal cancer ????Cancer J http://www.kidney.de/pget.php?&tw=1&pmid=24270349 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24270349 #FOAvip English Wikipedia <ref>{{Cite pmid|24270349}}</ref> Inflammatory mediator prostaglandin E2 in colorectal cancer #MMPMID24270349 Wang D; DuBois RN Cancer J 2013[Nov]; 19 (6): 502-10 PMID24270349show ga It is widely accepted that dietary fats and chronic inflammation are risk factors for developing colorectal cancer. Arachidonic acid is a major component of animal fats and the bioactive lipids produced from this substrate play critical roles in a variety of biologic processes, including cancer. Cyclooxygenase-derived prostaglandin E2 (PGE2) is a known pro-inflammatory lipid mediator and promotes tumor progression. Metabolism of arachidonic acid by the cyclooxygenase pathway provides one mechanism for the contribution of dietary fats and chronic inflammation to carcinogenesis. In this review, we highlight recent advances in our understanding of how pro-inflammatory mediator PGE2 promotes colorectal cancer immune evasion. These findings may provide a rationale for the development of new therapeutic approaches to subvert tumor-induced immunosuppression. äInflammatory mediator prostaglandin E2 in colorectal cancer (epmc).pdf DeepDyve Pubget Overpricing