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Clinical and microbiologic characteristics of vulvovaginitis in Korean
prepubertal girls, 2009-2014: a single center experience
#MMPMID27004204
Kim H
; Chai SM
; Ahn EH
; Lee MH
Obstet Gynecol Sci
2016[Mar]; 59
(2
): 130-6
PMID27004204
show ga
OBJECTIVE: To update information on the clinical and microbiologic
characteristics of pediatric vulvovaginitis in Korean prepubertal girls. METHODS:
A total of 120 girls (aged 0 to 9 years) with culture-confirmed pediatric
vulvovaginitis, diagnosed between 2009 and 2014, were enrolled in the study. The
epidemiologic and microbiologic characteristics, and clinical outcomes were
assessed. Patients with sexual precocity, as well as those who were referred for
suspected sexual abuse, were excluded. RESULTS: Girls aged 4 to 6 years were at
the highest risk of pediatric vulvovaginitis. Seasonal distribution indicated
obvious peaks in summer and winter. Of the 120 subjects, specific pathogens were
identified in the genital specimens in only 20 cases (16.7%). Streptococcus
pyogenes (n=12, 60%) was the leading cause of specific vulvovaginitis.
Haemophilus influenzae was isolated in one patient. No cases presented with
enteric pathogens, such as Shigella or Yersinia. A history of recent upper
respiratory tract infection, swimming, and bubble bath use was reported in 37.5%,
15.8%, and 10.0% of patients, respectively. Recent upper respiratory tract
infection was not significantly correlated with the detection of respiratory
pathogens in genital specimens (P>0.05). Of 104 patients who underwent perineal
hygienic care, 80 (76.9%) showed improvement of symptoms without antibiotic
treatment. Furthermore, the efficacy of hygienic care was not significantly
different between patients with or without specific pathogens (P>0.05).
CONCLUSION: Specific pathogens were only found in 16.7% of pediatric
vulvovaginitis cases. Our results indicate an excellent outcome with hygienic
care, irrespective of the presence of specific pathogens.