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10.1016/j.cobeha.2015.12.001 http://scihub22266oqcxt.onion/10.1016/j.cobeha.2015.12.001 C4795925!4795925!26998507     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Curr+Opin+Behav+Sci 2016 ; 9 (ä): 40-6 Nephropedia Template TP {{tp|p=26998507|t=2016. The Outward Spiral: A vicious cycle model of obesity and cognitive dysfunction |pdf=|usr=}}{{26998507}} gab.com Text The Outward Spiral: A vicious cycle model of obesity and cognitive dysfunction JO: Curr Opin Behav Sci http://www.kidney.de/pget.php?&tw=1&pmid=26998507 #FOAvip Chronic failure to suppress intake during states of positive energy balance leads to weight gain and obesity. The ability to use context ? including interoceptive satiety states ? to inhibit responding to previously rewarded cues appears to depend on the functional integrity of the hippocampus. Recent evidence implicates energy dense Western diets in several types of hippocampal dysfunction, including reduced expression of neurotrophins and nutrient transporters, increased inflammation, microglial activation, and blood brain barrier permeability. The functional consequences of such insults include impairments in an animal?s ability to modulate responding to a previously reinforced cues. We propose that such deficits promote overeating, which can further exacerbate hippocampal dysfunction and thus initiate a vicious cycle of both obesity and progressive cognitive decline. Twit Text FOAVip The Outward Spiral: A vicious cycle model of obesity and cognitive dysfunction ????Curr Opin Behav Sci http://www.kidney.de/pget.php?&tw=1&pmid=26998507 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26998507 #FOAvip English Wikipedia <ref>{{Cite pmid|26998507}}</ref> The Outward Spiral: A vicious cycle model of obesity and cognitive dysfunction #MMPMID26998507 Hargrave SL; Jones S; Davidson TL Curr Opin Behav Sci 2016[Jun]; 9 (ä): 40-6 PMID26998507show ga Chronic failure to suppress intake during states of positive energy balance leads to weight gain and obesity. The ability to use context ? including interoceptive satiety states ? to inhibit responding to previously rewarded cues appears to depend on the functional integrity of the hippocampus. Recent evidence implicates energy dense Western diets in several types of hippocampal dysfunction, including reduced expression of neurotrophins and nutrient transporters, increased inflammation, microglial activation, and blood brain barrier permeability. The functional consequences of such insults include impairments in an animal?s ability to modulate responding to a previously reinforced cues. We propose that such deficits promote overeating, which can further exacerbate hippocampal dysfunction and thus initiate a vicious cycle of both obesity and progressive cognitive decline. äThe Outward Spiral: A vicious cycle model of obesity and cognitive dys(epmc).pdf DeepDyve Pubget Overpricing