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10.1155/2016/2015251

http://scihub22266oqcxt.onion/10.1155/2016/2015251
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suck abstract from ncbi


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pmid27042657
      Biomed+Res+Int 2016 ; 2016 (ä): 2015251
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  • Clinical Characteristics and 30-Day Outcomes of Intermittent Hemodialysis for Acute Kidney Injury in an African Intensive Care Unit #MMPMID27042657
  • Kwizera A ; Tumukunde J ; Ssemogerere L ; Ayebale E ; Agaba P ; Yakubu J ; Lubikire A ; Nabukenya M ; Kalyesubula R
  • Biomed Res Int 2016[]; 2016 (ä): 2015251 PMID27042657 show ga
  • INTRODUCTION: Acute kidney injury (AKI) is a common occurrence in the intensive care unit (ICU). Studies have looked at outcomes of renal replacement therapy using intermittent haemodialysis (IHD) in ICUs with varying results. Little is known about the outcomes of using IHD in resource-limited settings where continuous renal replacement therapy (CRRT) is limited. We sought to determine outcomes of IHD among critically ill patients admitted to a low-income country ICU. METHODS: A retrospective review of patient records was conducted. Patients admitted to the ICU who underwent IHD for AKI were included in the study. Patients' demographic and clinical characteristics, cause of AKI, laboratory parameters, haemodialysis characteristics, and survival were interpreted and analyzed. Primary outcome was mortality. RESULTS: Of 62 patients, 40 had complete records. Median age of patients was 38.5 years. Etiologic diagnoses associated with AKI included sepsis, malaria, and ARDS. Mortality was 52.5%. APACHE II (OR 4.550; 95% CI 1.2-17.5, p = 0.028), mechanical ventilation (OR 13.063; 95% CI 2.3-72, p = 0.003), and need for vasopressors (OR 16.8; 95% CI 3.4-82.6, p = 0.001) had statistically significant association with mortality. CONCLUSION: IHD may be a feasible alternative for RRT in critically ill haemodynamically stable patients in low resource settings where CRRT may not be available.
  • |APACHE [MESH]
  • |Acute Kidney Injury/epidemiology/physiopathology/*therapy [MESH]
  • |Adult [MESH]
  • |Africa [MESH]
  • |Aged [MESH]
  • |Critical Illness [MESH]
  • |Female [MESH]
  • |Humans [MESH]
  • |Intensive Care Units [MESH]
  • |Male [MESH]
  • |Middle Aged [MESH]
  • |Renal Dialysis/adverse effects/*methods [MESH]
  • |Renal Replacement Therapy/methods [MESH]


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