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Deprecated: Implicit conversion from float 225.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Urology 2016 ; 89 (ä): 118-22 Nephropedia Template TP
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Trends in Sickle-Cell-Disease-Related Priapism in U S Children s Hospitals #MMPMID26674747
Wang HHS; Herbst KW; Rothman JA; Shah NR; Wiener JS; Routh JC
Urology 2016[Mar]; 89 (ä): 118-22 PMID26674747show ga
Objective: To define rates of priapism diagnosis and inpatient admission among males with SCD. Methods: We retrospectively reviewed the Pediatric Health Information System database for males aged <21 years treated 2004-2012. We identified patients with SCD and priapism based on ICD-9-CM diagnosis codes. Logistic regression and generalized estimating equation models were used to control for confounding and to adjust for within-hospital clustering of similar patients. Results: We identified 17,186 males who were admitted 137,710 times during the study period. Of these, 362 (2.1%) were diagnosed with priapism on 748 admissions. There was a significant decrease in the number of priapism admissions among patients with SCD over time (0.81% in 2004 to 0.44% in 2012, p<0.001). The number of patients diagnosed with SCD-related priapism varied over time without a statistically significant trend (2.3% in 2004, 2.69% in 2008, 1.01% in 2012, p=0.34). Rates of priapism admissions (0-4.4%) varied widely between hospitals. Older patient age was associated with an increased likelihood of a priapism admission in the multivariate logistic regression model after adjusting for treatment year, hospital region, and for hospital-level clustering of similar patients. Conclusions: From 2004-2012, the number of admissions for SCD-related priapism declined while the number of individual patients diagnosed with SCD-related priapism did not. Rates of priapism-related admissions in males with SCD vary widely among PHIS hospitals.